Results 61 to 70 of about 7,712,805 (262)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Implementation of tuberculosis intensive case finding, isoniazid preventive therapy, and infection control ("Three I's") and HIV-tuberculosis service integration in lower income countries [PDF]

, 2016
World Health Organization advocates for integration of HIV-tuberculosis (TB) services and recommends intensive case finding (ICF), isoniazid preventive therapy (IPT), and infection control ("Three I's") for TB prevention and control among persons living ...
M Katherine Charles, Barbara Castelnuovo (10700), Nguyen Thi Dung, Divine Avit-Edi, Cortés Moncada, Claudia, IeDEA, Ballif, Marie, Nakigozi, Gertrude, Marie Ballif, Durier, Nicolas, Dusingize, Jean Claude, Charles, M Katherine, Nguyen, Thi Dung, Wester, C William, ,, Meridith Blevins, Dung, Nguyen Thi, Cortes, Claudia P, Cortes, Claudia P., Fenner, Lukas, C William Wester, Wester, C. William, Jean Claude Dusingize (473718), Divine Avit-Edi (2609464), Claudia P. Cortes (473719), Mary Lou Lindegren (2609461), Lindegren, Mary Lou, Gertrude Nakigozi, Charles, M. Katherine, Gertrude Nakigozi (247948), C. William Wester (250717), Timothy R. Sterling (148936), Lukas Fenner, Marie Ballif (368655), Blevins, Meridith, Nicolas Durier (326615), Jean Claude Dusingize, Claudia P Cortes, Avit-Edi, Divine, Sterling, Timothy R., Nguyen Thi Dung (245054), Nicolas Durier, Castelnuovo, Barbara, Timothy R Sterling, International epidemiology Databases to Evaluate AIDS (IeDEA) Collaboration, Mary Lou Lindegren, Barbara Castelnuovo, Lukas Fenner (149822), Sterling, Timothy R, Meridith Blevins (291088), M. Katherine Charles (2609458)   +50 more
core   +3 more sources

Combining AlphaFold—based AI docking with omics technologies preliminarily unveils the mechanism of Guominkang in treating allergic rhinitis

Scientific Reports
Allergic rhinitis (AR) is a common immune-mediated chronic inflammatory disease with a complex pathogenesis involving multiple responses of the immune system and epigenetic changes.
Yumei Zhou, Longmei Yu, Haiyun Zhang, Juntong Liu, Honglei Zhang, Linhan Hu, Ji Wang, Qi Wang   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Issa N Ouédraogo, Tiono, Alfred B, Youssouf Kaboré, Daniel Chandramohan, Yaro Jean Baptiste, Ouédraogo, Amidou Z, Soulama, Issiaka, Konaté Amadou T., Issa N. Ouédraogo, Ouédraogo Issa N., Amadou T Konaté, Yaro, Jean Baptiste, Gansané, Adama, Ouédraogo Espérance, Alfred B. Tiono, Jean Baptiste Yaro, Diadier A. Diallo, Greenwood, Brian, Diallo Diadier A., Espérance Ouédraogo, Chandramohan Daniel, Ouédraogo, Alphonse, Cousens, Simon, Diadier A Diallo, Greenwood Brian, Alfred B Tiono, David T. Kangoyé, Ouédraogo, Espérance, Chandramohan, Daniel, Paul J Milligan, Kaboré, Youssouf, Ouédraogo Alphonse, Amadou T. Konaté, Sirima Sodiomon B., Amidou Z Ouédraogo, Kangoyé, David T, Sirima, Sodiomon B, Diarra, Amidou, Ouédraogo, Issa N, Paul J. Milligan, Sodiomon B. Sirima, Kangoyé David T., Milligan Paul J., Milligan, Paul J, Cousens Simon, Alphonse Ouédraogo, Simon Cousens, Diallo, Diadier A, Brian Greenwood, Amidou Z. Ouédraogo, Adama Gansané, Tiono Alfred B., Kaboré Youssouf, Sodiomon B Sirima, Gansané Adama, David T Kangoyé, Issiaka Soulama, Ouédraogo Amidou Z., Soulama Issiaka, Amidou Diarra, Konaté, Amadou T, Diarra Amidou   +61 more
core   +1 more source

Course Of Pregnancy, Delivery And Health State Of Newborns After Preventive Treatment Of Gestosis In Pregnant Women Of Risk Group [PDF]

Саратовский научно-медицинский журнал, 2009
The research objective is to decrease the frequency of perinatal complications in mother, fetus and newborn. Methodology used is prospective study. Course of pregnancy, delivery, postnatal period and neonatal period has been studied at 50 women and ...
N.I. Zryachkin, L.V. Vasilenko, O.S. Odnokozova   +2 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications. [PDF]

, 2007
BACKGROUND\ud \ud Intermittent preventive treatment (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different estimates of clinical malaria protection in two trials that used the same protocol in Ifakara, Tanzania, and Manhiça ...
Sacarlal, Jahit, Schellenberg, David, Pedro Aide, Aide, Pedro, David Schellenberg, Kahigwa, Elizeus, Sanz, Sergi, Elizeus Kahigwa, Aponte, John J, Macete, Eusebio, Menendez, Clara, Clara Menendez, Marcel Tanner, Hassan Mshinda, Alonso, Pedro L, Eusebio Macete, Sergi Sanz, John J Aponte, Pedro L Alonso, Jahit Sacarlal, Mshinda, Hassan, Tanner, Marcel   +21 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source