Results 81 to 90 of about 7,712,805 (262)

Isoniazid preventive therapy and risk for resistant tuberculosis. [PDF]

, 2006
In the context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly promoted, but concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its widespread implementation.
Grant, Alison D, Balcells, Maria Elvira, Thomas, Sara L, Peter Godfrey-Faussett, Maria Elvira Balcells, Godfrey-Faussett, Peter, Sara L. Thomas, Alison D. Grant   +7 more
core   +1 more source

Field Trial and Performance Evaluation of Soybean-Based Bio-Fog Seals for Asphalt Rejuvenation

Applied Sciences
Cracked and deteriorated asphalt are common problems on our roads, leading to safety concerns and requiring significant resources for rehabilitation and reconstruction.
Ana Luiza Rodrigues, Caio Falcao, Maxwell Staver, Irvin Pinto, Andrew Becker, Michael Forrester, Austin Hohmann, Baker Kuehl, Nacu Hernandez, Ashley Buss, Eric Cochran, R. Christopher Williams   +11 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children : a cluster-randomised controlled trial [PDF]

, 2015
Iron deficiency (ID) and malaria co-exist in tropical regions and both contribute to high rates of anaemia in young children. It is unclear whether iron fortification combined with intermittent preventive treatment (IPT) of malaria would be an ...
Righetti, Aurélie A., Eliézer K. N’Goran, Brittenham, Gary M, Utzinger, Jürg, Victorine G. Diakité, Wegmüller, Rita, Adiossan, Lukas G, Rita Wegmüller, Dominik Glinz, Zimmermann, Michael B, Lukas G. Adiossan, Brittenham, Gary M., Burkhardt Seifert, Jürg Utzinger, Aurélie A. Righetti, Zimmermann, Michael B., Seifert, Burkhardt, Diakité, Victorine G., Mamadou Ouattara, Adiossan, Lukas G., Michael B. Zimmermann, Hurrell, Richard F, Richard F. Hurrell, Glinz, Dominik, Righetti, Aurélie A, Ouattara, Mamadou, N'Goran, Eliézer K., Diakité, Victorine G, Hurrell, Richard F., N'Goran, Eliézer K, Gary M. Brittenham   +30 more
core   +1 more source

A Human Body Simulation Using Semantic Segmentation and Image-Based Reconstruction Techniques for Personalized Healthcare

Applied Sciences
The global healthcare market is expanding, with a particular focus on personalized care for individuals who are unable to leave their homes due to the COVID-19 pandemic.
Junyong So, Sekyoung Youm, Sojung Kim
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Brokering the boundary between science and advocacy: the case of intermittent preventive treatment among infants. [PDF]

, 2013
The process of translating research into policy has gained considerable attention in recent years and a number of studies have investigated the nexus between the two 'worlds' of research and policy.
Cruz, Valeria Oliveira, Walt, Gill
core   +1 more source

STRUCTURAL TRANSFORMATIONS IN AXILLARY AND MESENTERIC LYMPH NODES IN CHEMOTHERAPY AND SURGICAL TREATMENT OF EXPERIMENTAL MAMMARY TUMOR

Сибирский научный медицинский журнал, 2019
Was conducted histological study axillary and mesenteric lymph nodes in breast cancer induced by intramammary administration of N-methyl-N-nitrosourea, chemotherapy according to the CMF scheme (cyclophosphamide, methotrexate, 5-fluorouracil), operative ...
O. V. Kazakov, A. V. Kabakov, A. F. Poveshchenko, T. V. Rayter, D. N. Strunkin, A. P. Lykov, V. I. Konenkov   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Lamotrigine prophylaxis is associated with reduced aura frequency in patients with burdensome migraine aura: a retrospective observational study

Frontiers in Neurology
IntroductionMigraine aura affects approximately one-third of migraine patients. In some individuals, aura remains highly disabling due to the lack of effective, targeted treatment options.
Sena Uzun, Sena Uzun, Sena Uzun, Ulf Frejvall, Hulya Karatas, Hulya Karatas, Per Petersson, Per Petersson, Gürdal Sahin, Gürdal Sahin   +9 more
doaj   +1 more source