Results 61 to 70 of about 66,525 (297)

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

open access: yesAdvanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Isomaltooligosaccharides Sustain the Growth of Prevotella Both In Vitro and in Animal Models

open access: yesMicrobiology Spectrum, 2022
The human digestive tract is colonized by trillions of bacterial cells that play important roles in human health and diseases. It is well known that dietary habits are associated with human microbiota enterotypes.
Junkui Chen   +12 more
doaj   +1 more source

Abundance of genera within the phylum Firmicutes compared to the genus Prevotella.

open access: yes, 2014
Stack bar showing the abundance of genera belonging to the phylum Firmicutes that were negatively correlated with Prevotella abundance. These included all genera that were in at least half of the cows sampled and constituted 0.1% of the reads in at least
Itzhak Mizrahi (177643)   +2 more
core   +1 more source

Modulation der intestinalen Homöostase und Entzündung durch Prevotella intestinalis (nov. sp.) [PDF]

open access: yes, 2018
Intestinal homeostasis is maintained by the dynamic interplay between the gut microbiota and the host immune system. Alterations in the composition and function of the gut microbiota have been associated with increased susceptibility to intestinal ...
Iljazovic, Aida
core   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Modulation of inflammatory responses by gastrointestinal Prevotella spp. – From associations to functional studies

open access: yesInternational Journal of Medical Microbiology, 2021
Numerous studies have associated alterations in the gut microbiota composition with almost every known inflammatory disease. However, proving the biological relevance of distinct microbial signatures and linking specific microorganisms to host phenotypes,
Aida Iljazovic   +4 more
doaj   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li   +15 more
wiley   +1 more source

Additional file 6: of An exploration of Prevotella-rich microbiomes in HIV and men who have sex with men

open access: yes, 2018
Figure S3. Samples are best divided into two enterotypes, which are primarily defined by Bacteroides or Prevotella richness. A. Silhouette analysis shows that two clusters is the most efficient way to divide the data. B.
Nichole Nusbacher (5933339)   +11 more
core   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang   +7 more
wiley   +1 more source

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