Results 81 to 90 of about 1,043,331 (298)

Embedded System for Interactive Pneumatic Hand Rehabilitation: Real-Time Gaming Interface With Cognitive Stimulation for Motor Recovery

open access: yesIEEE Access
Restoring fine motor skills in individuals with upper extremity sensory-motor post-stroke impairments necessitates repetitive, task-specific exercises to promote functional recovery.
Narges Ghobadi   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Exploring the Frontier of 3D Bioprinting for Tendon Regeneration: A Review

open access: yesEng
The technology of 3D bioprinting has sparked interest in improving tendon repair and regeneration, promoting quality of life. To perform this procedure, surgical intervention is often necessary to restore functional capacity.
Josée Rosset   +4 more
doaj   +1 more source

Structural insights into a high-fidelity CRISPR-Cas12a variant revealed using optimized graphene oxide cryo-EM grids [PDF]

open access: yesStructural Dynamics
CRISPR-Cas12a has become a widely used tool for genome editing and molecular diagnostics. However, unintended off-target DNA cleavage by Cas12a remains a key limitation. To address this, our lab engineered a Cas12a variant by modifying the bridge helix—a
Chhandosee Ganguly   +3 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

RFID Sensor with Integrated Energy Harvesting for Wireless Measurement of dc Magnetic Fields

open access: yesSensors
High-voltage direct-current (HVdc) transmission lines are gaining more attention as an integral part of modern power system networks. Monitoring the dc current is important for metering and the development of dynamic line rating control schemes. However,
Shijie Fu, Greg E. Bridges, Behzad Kordi
doaj   +1 more source

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