Results 21 to 30 of about 3,541 (157)

Genome-Wide Association Study (GWAS) for Examining the Genomics Controlling Prickle Production in Red Raspberry (Rubus idaeus L.)

open access: yesAgronomy, 2020
Red raspberry (Rubus idaeus L.) is an expanding high-value berry crop worldwide. The presence of prickles, outgrowths of epidermal tissues lacking vasculature, on the canes, petioles, and undersides of leaves complicates both field management and harvest.
Archana Khadgi, Courtney A. Weber
doaj   +1 more source

Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled

open access: yesCells, 2020
Wnt and BMP signaling pathways are two key molecular machineries regulating development and homeostasis. The efficient coordination of Wnt and BMP is essential in many developmental processes such as establishment of antero-posterior and dorso-ventral ...
Ondrej Bernatik   +3 more
doaj   +1 more source

Coordination of planar cell polarity pathways through Spiny-legs

open access: yeseLife, 2015
Morphogenesis and physiology of tissues and organs requires planar cell polarity (PCP) systems that orient and coordinate cells and their behaviors, but the relationship between PCP systems has been controversial.
Abhijit A Ambegaonkar, Kenneth D Irvine
doaj   +1 more source

Downregulation of oxidative stress-mediated glial innate immune response suppresses seizures in a fly epilepsy model

open access: yesCell Reports, 2023
Summary: Previous work in our laboratory has shown that mutations in prickle (pk) cause myoclonic-like seizures and ataxia in Drosophila, similar to what is observed in humans carrying mutations in orthologous PRICKLE genes.
Krishna M. Nukala   +5 more
doaj   +1 more source

Genome‐wide identification of HD‐ZIP gene family and screening of genes related to prickle development in Zanthoxylum armatum

open access: yesThe Plant Genome, 2023
Zanthoxylum armatum is an important cash crop for medicinal and food purposes in Asia. However, its stems and leaves are covered with a large number of prickles, which cause many problems in the production process. The homeodomain leucine zipper (HD‐ZIP)
Xiaoxi Zhang   +10 more
doaj   +1 more source

Epilepsy gene prickle ensures neuropil glial ensheathment through regulating cell adhesion molecules

open access: yesiScience, 2023
Summary: Human PRICKLE1 gene has been associated with epilepsy. However, the underlying pathogenetic mechanisms remain elusive. Here we report a Drosophila prickle mutant pkIG1-1 exhibiting strong epileptic seizures and, intriguingly, abnormal glial ...
Yanbo Chen   +6 more
doaj   +1 more source

A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans. [PDF]

open access: yesPLoS ONE, 2016
Genetic pathways that regulate nascent neurite formation play a critical role in neuronal morphogenesis. The core planar cell polarity components VANG-1/Van Gogh and PRKL-1/Prickle are involved in blocking inappropriate neurite formation in a subset of ...
David Carr   +7 more
doaj   +1 more source

Silicon Alters Leaf Surface Morphology and Suppresses Insect Herbivory in a Model Grass Species

open access: yesPlants, 2020
Grasses accumulate large amounts of silicon (Si) which is deposited in trichomes, specialised silica cells and cell walls. This may increase leaf toughness and reduce cell rupture, palatability and digestion.
Casey R. Hall   +3 more
doaj   +1 more source

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