Results 141 to 150 of about 83,365 (272)

Adrenal Insufficiency During Treatment With Immune‐Checkpoint Inhibitors: How to Simplify the Diagnostic Pathway?

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective and Background Early identification of adrenal insufficiency (AI) during immune‐checkpoint inhibitors (ICIs) is crucial to prevent life‐threatening consequences; however, the diagnosis is challenging. Design, Patients and Measurement In this prospective observational study, ICI‐treated cancer patients with morning serum cortisol (SC)
Alice Nervo   +6 more
wiley   +1 more source

Mass Spectrometric Measurements of 11‐Deoxycortisol, Androstenedione and Dehydroepiandrosterone Are Superior to Cortisol to Assess Selectivity of Non‐Stimulated Adrenal Vein Sampling

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Successful adrenal venous sampling (AVS) is traditionally assessed using the ratio of cortisol in adrenal to peripheral venous plasma to calculate the selectivity index. With mass spectrometry other steroids can be simultaneously measured that may improve numbers of apparent successful sampling procedures.
Francesco Alessi   +14 more
wiley   +1 more source

COVID-19 Infection in Adrenal Tuberculosis Patients with Adrenal Insufficiency Who Complicated with Adrenal Crisis

open access: yesActa Medica Indonesiana
Adrenal insufficiency can increase the risk of infection. Respiratory infections play a role in the greater number of mortalities in patients with primary adrenal insufficiency.
Matdoan Rifkiah Aisyah   +3 more
doaj   +2 more sources

Complete recovery after glucocorticoid replacement therapy in a case of primary adrenal insufficiency caused by adrenal tuberculosis infection [PDF]

open access: gold, 2023
Hendra Zufry   +5 more
openalex   +1 more source

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri   +6 more
wiley   +1 more source

Efficacy and Tolerability of Metyrapone in Mild Autonomous Cortisol Secretion: Real‐World Findings From Clinical Practice

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Mild autonomous cortisol secretion (MACS) is associated with increased cardiometabolic risk factors including hypertension, type 2 diabetes and dyslipidaemia. By using evening doses of metyrapone, a short‐acting 11‐β hydroxylase inhibitor, it has been shown that it is possible to reset the abnormal circadian cortisol rhythm in MACS ...
Simon Berry   +3 more
wiley   +1 more source

Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency

open access: yesClinical Genetics, EarlyView.
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou   +3 more
wiley   +1 more source

Psychiatric effects of GLP‐1 receptor agonists: A systematic review of emerging evidence

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract This systematic review examines the current literature on glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs)‐associated psychiatric manifestations, including depression, suicidality, eating disorders, substance use disorders (SUD) and schizophrenia spectrum disorders.
Brianna Sa   +7 more
wiley   +1 more source

Effectiveness and safety of GLP‐1 receptor agonists in craniopharyngioma patients with obesity: A multicentre real‐world study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Acquired hypothalamic obesity (aHO) following craniopharyngioma (CP) is a challenging condition with limited therapeutic options. This study aimed to assess the real‐world effectiveness and safety of GLP‐1 RAs in this population. Materials and Methods CranioGLP1 is a retrospective multicentre study including 116 adults with aHO treated ...
Flora Lambert   +28 more
wiley   +1 more source

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