Results 151 to 160 of about 37,111 (253)

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Mineralocorticoid effects of fludrocortisone and hydrocortisone in primary adrenal insufficiency: EU-AIR patient data. [PDF]

J Endocrinol Invest
Ekman B, Quinkler M, Zhang P, Isidori AM, Murray RD, Wahlberg J, EU-AIR investigators.   +6 more
europepmc   +1 more source

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber, Roemer B. Brandt, Mariël Leon Morales‐Grooters, Ronald van der Wal, Sjoerd A. A. van den Berg, Jelle J. Goeman, Antoinette Maassen van den Brink, Rolf Fronczek   +7 more
wiley   +1 more source

Concomitant Immune Checkpoint Inhibitors Induced Central and Primary Adrenal Insufficiency: A Diagnostic Challenge. [PDF]

JCEM Case Rep
Nascè A, Leboulleux S, Chiriac S, Tsantoulis P, Mavromati M.   +4 more
europepmc   +1 more source

Pretreatment of keratinocytes with Galactomyces ferment filtrate (GFF) promotes stress resiliency in an in vitro oxidative stress model

International Journal of Cosmetic Science, EarlyView.
GFF pretreatment enhances keratinocyte protection against oxidative stress by mitigating stress‐induced biomolecular changes and gene expression dysregulation. GFF‐pretreated keratinocytes maintain healthy epidermal biology post‐stress, preserving mitochondrial function and proliferative capacity.
Lisa C. Green, Tim Reichling, Holly A. Rovito, Jodie Reed, Xingtao Wei, John M. Snowball, Tom Cambron, Tomohiro Hakozaki   +7 more
wiley   +1 more source

Normal Immune Function in a Newborn With Early Identification of a <i>SAMD9</i> Mutation Presenting With Growth Restriction, Thrombocytopenia, and Primary Adrenal Insufficiency. [PDF]

Clin Case Rep
Gao KM, Huang QYJ, Huang P, Muzaffar A, Beheshti R, Wood R, Dantzer J, Gutierrez MJ.   +7 more
europepmc   +1 more source

Improving primary aldosteronism diagnosis and treatment: outcomes from an endocrine hypertension service

Internal Medicine Journal, EarlyView.
Abstract Aims To evaluate the sustained impact of the Endocrine Hypertension Service on primary aldosteronism (PA) diagnosis and management over a subsequent 3‐year period. Background PA is a prevalent yet underdiagnosed cause of secondary hypertension, associated with increased cardiovascular, renal and metabolic risk. Limited awareness, resources and
Minn W. Chow, Chrislyn Ng, Jimmy Shen, Peter J. Fuller, Jun Yang, Renata Libianto   +5 more
wiley   +1 more source

Identifying Knowledge Gaps in Individuals With Primary Adrenal Insufficiency: A Critical Step in Preventing Adrenal Crisis. [PDF]

Clin Endocrinol (Oxf)
Ross IL, Llahana S, Anderson MM, Demeke B, Minnie EM, Wass JAH, Henry M.   +6 more
europepmc   +1 more source

Determinant Factors of Self‐Care Deficit in People With Chronic Wounds: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify and synthesise the scientific evidence on determinants of self‐care deficits in people with chronic wounds. Design Scoping review based on the Joanna Briggs Institute guidelines. Methods This scoping review was conducted by a review team responsible for study screening, data extraction and synthesis.
Janislei Soares Dantas, Yan Lincoln Mamede Gomes, Ana Clara de Macedo Farias Ramos, Selene Cordeiro Vasconcelos, Maria Eliane Moreira Freire   +4 more
wiley   +1 more source

Laparoscopic sleeve gastrectomy in a patient with primary adrenal insufficiency: a case report. [PDF]

J Surg Case Rep
Nemri AA, Alshehri K, Alshahrani A, Abdulhaq M, Alageel AH.   +4 more
europepmc   +1 more source