Results 141 to 150 of about 37,111 (253)

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

How Common Is Hypercortisolism in Patients With Hypertension? Risk Factors, Epidemiology, and Making a Diagnosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley   +1 more source

Late-Onset NR0B1-Related Adrenal Hypoplasia Congenita Presenting With Primary Adrenal Insufficiency and Pubertal Delay. [PDF]

Cureus
Nico JF, Cardoso R, Mirante A.
europepmc   +1 more source

Absence of Interaction Between 5α‐Reductase Inhibitors and Glucocorticoids on Incidence of Myocardial Infarction in People With Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims People with Type 2 diabetes experience higher cardiometabolic risk, and both synthetic glucocorticoids and use of 5α‐reductase inhibitors have been individually linked to increased risk of myocardial infarction. We tested whether the increase in risk is exacerbated by co‐prescription of both drugs.
Haolan Tu, Chengsheng Ju, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Scottish Diabetes Research Network Epidemiology Group, Peter Hanlon, Robert Lindsay, David McAllister, John Petrie, Naveed Sattar, Brian Kennon, Sam Philip, Scott Cunningham, Huan Wang, William Berthon, Helen Colhoun, Paul McKeigue, Sarah Wild, Ewan R. Pearson, Li Wei, Ruth Andrew   +20 more
wiley   +1 more source

Management of Primary Adrenal Insufficiency and Overt Hypothyroidism in an HIV-Positive Patient in a Resource-Limited Setting: A Case Report. [PDF]

Clin Case Rep
Edward M, John W, Raphael DM.
europepmc   +1 more source

Is Hypercortisolism Treatable? Which Patients Should Be Treated and How—A Practical Guide for Clinicians

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley   +1 more source

Posaconazole-induced primary adrenal insufficiency concomitant with pseudoaldosteronism under normal blood pressure. [PDF]

Endocrinol Diabetes Metab Case Rep
Katsumata M, Miura M, Masuzawa M.
europepmc   +1 more source

Primary adrenal insufficiency in adults

Cleveland Clinic Journal of Medicine
openaire   +2 more sources

Unraveling the upward intergenerational link between adolescent depression and maternal health in later life

Family Relations, EarlyView.
Abstract Objective This study investigated whether depressive symptoms in adolescence are associated with mother's physical health in later life. It further explored the potential mechanisms underlying this relationship, focusing on psychological, behavioral, and healthcare‐related pathways.
Keun Young Kwon, Hayun Jang, Jinho Kim
wiley   +1 more source

Autoimmune Primary Adrenal Insufficiency in a Pregnant Patient Without Autoimmune Comorbidities. [PDF]

AACE Endocrinol Diabetes
Reyes NA, McDonald V, Culver SA.
europepmc   +1 more source