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Primary aldosteronism

Trends in Cardiovascular Medicine, 2016
In 1955 Dr Jerome Conn first documented primary aldosteronism (PA). Since then, screening, diagnosis and treatment have developed, in the process both refining and complicating management. Currently, screening requires 4-6 weeks of lead-up, including major changes in antihypertensive therapy, followed by a blood draw for plasma aldosterone ...
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Primary aldosteronism

Current Cardiology Reports, 2007
Primary aldosteronism is one of the few potentially curable forms of hypertension. This article highlights recent advances in the pathophysiology, diagnosis, and treatment of this relatively common secondary form of hypertension. These topics include the recognition that this disorder is more prevalent than previously assumed, the identification of ...
Richard J, Auchus, Fiemu E, Nwariaku
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Subclinical primary aldosteronism

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
Screening for primary aldosteronism was historically recommended in patients with moderate to severe and/or resistant hypertension. Patients with mild hypertension and normotensive subjects were therefore excluded from the screening. However, a considerable number of normotensive individuals without hypokalaemia may have subclinical forms of primary ...
Yuji, Ito   +2 more
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Primary Aldosteronism

Urologic Clinics of North America, 1988
Primary aldosteronism remains a diagnostic challenge. Despite the availability of sensitive and specific immunoassay techniques, the simplification of diagnostic testing, and the introduction of sensitive imaging techniques, there remain uncertainties about the optimal methods of screening, the sensitivity and specificity of various tests, diagnostic ...
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"Normotensive" Primary Aldosteronism

Annals of Internal Medicine, 1978
Excerpt Hypokalemia and hypertension are the most important features of primary aldosteronism. In rare instances, patients with this disorder have normal serum potassium levels, but this is usually...
R D, Zipser, P F, Speckart
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Normotensive primary aldosteronism

The American Journal of Medicine, 1980
A very unusual case of normotensive primary aldosteronism is described. A 25 year old woman first noticed numbness of both hands followed by a typical tetany attack. The blood pressure was within normal ranges. The results of other physical examinations were negative except for the findings of Trousseau's sign. Hypokalemi, increased potassium clearance,
H, Shiroto   +6 more
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PREGNANCY AND PRIMARY ALDOSTERONISM

Obstetrical & Gynecological Survey, 1967
ABSTRACT A case is reported of a 32-yr-old woman with primary aldosteronism in whom metabolic and blood pressure abnormalities were improved during pregnancy. Aldosterone secretion increased throughout pregnancy, as did the acid-labile conjugate of aldosterone-tetrahydroaldosterone ratio, but no complications occurred.
E G, Biglieri, P E, Slaton
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Subclinical Primary Aldosteronism

Annals of Internal Medicine, 2017
The editorialist discusses Brown and colleagues' study, noting that primary aldosteronism may occur frequently before development of hypertension and deserves more diagnostic attention than it now ...
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Primary aldosteronism and aldosterone-associated hypertension

Journal of Clinical Pathology, 2008
The field of primary aldosteronism (PA) and aldosterone-related hypertension has undergone rapid evolution. From a relatively rare curiosity PA has become a common problem particularly in selected hypertensive populations. Patients with PA and aldosterone-related hypertension appear to be at higher cardiovascular and renal risk than comparable patients
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Detecting and treating primary aldosteronism: primary aldosteronism.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2007
Primary aldosteronism (PA) is the most common cause of mineralocorticoid hypertension. Different studies, using the plasma aldosterone concentration to plasma renin activity ratio (PAC/PRA) for the screening of patients with hypertension, have shown a marked increase in the detection rate of PA.
MANTERO, FRANCO   +2 more
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