Results 81 to 90 of about 23,028 (267)

Targeting Cryptochromes in Chronic Diseases

Cell Biology International, Volume 49, Issue 12, Page 1579-1590, December 2025.
ABSTRACT The circadian clock generates 24‐h molecular rhythms through transcription–translation negative feedback loops (TTFLs) and regulates daily physiological processes such as sleep–wake cycles, body temperature, hormone secretion, metabolism, and immune function.
Takuro Toda, Tsuyoshi Hirota
wiley   +1 more source

Concepts actuels de l'hyperaldostéronisme primaire [PDF]

, 2010
peer ...
Beckers, Albert, Hamoir, Etienne, Krzesinski, Jean-Marie, Maweja, Sylvie, Vroonen, Laurent   +4 more
core  

The syndromes of low-renin hypertension: separating the wheat from the chaff [PDF]

, 2004
Primary aldosteronism (PA) is characterized by hypertension and suppressed renin activity with or without hypokalemia and comprises the aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia or idiopatic hyperaldosteronism (IHA). In recent
Biglieri, Edward G., Kater, Claudio Elias   +1 more
core   +4 more sources

Diagnostic Challenges of Adrenal Venous Sampling for Primary Hyperaldosteronism in a Patient With Subclinical Cushing's Syndrome: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Hypertension is a significant comorbidity in the New World, and its prevalence is rising. Around 5%–10% of cases with hypertension have secondary hypertension. Adrenal gland disease is among the common causes of secondary hypertension. We present a 57‐year‐old male with uncontrolled hypertension and a history of intracranial hemorrhage.
Mahsa Malekian, Vahide Sadra, Amir Bahrami, Javad Jalili, Hamidreza Ashayeri   +4 more
wiley   +1 more source

Primary Aldosteronism Takes (KCNJ)Five! [PDF]

, 2012
International ...
Zennaro, Maria-Christina
core   +3 more sources

Clinical significance of parathyroid hormone in mineral and glucose metabolism disorders among patients with primary aldosteronism

SAGE Open Medicine
Objective: To investigate the differences in mineral and glucose metabolic disorders among patients with primary aldosteronism, nonfunctional adrenal tumors, and controls. Methods: A retrospective analysis was conducted on clinical data from 578 patients,
Zhilian Sun, Wenxiu Liu
doaj   +1 more source

Adrenal computed tomography and NP-59 usefulness for diagnosing aldosterone-producing adenomas and idiopathic hyperaldosteronism in primary hyperaldosteronism

Urological Science, 2016
Objectives: Two major causes of primary aldosteronism are aldosterone-producing adenomas (APA) and idiopathic hyperaldosteronism (IHA). In this study, we attempted to determine the role of NP-59 in identifying APA prior to adrenalectomy, especially when ...
Ting-Po Lin, Allen W. Chiu, Marcelo Chen, Che-Hao Weng, Pei-Yin Ho, Jong-Ming Hsu, Wun-Rong Lin   +6 more
doaj   +1 more source

Saliva as a TDM Matrix and Its Application in the Model‐Informed Precision Dosing

The Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1650-1660, December 2025.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu, Yujie Wen, Jinxia Lu, Maobai Liu, Xin Luo, Wei Huang, Helin Xie, Yu Cheng, Hongqiang Qiu, Xuemei Wu   +9 more
wiley   +1 more source

Primary aldosteronism diagnosis in the intensive care unit: resistant alkalosis and hypokalemia during severe sepsis with hyperlactatemia: a case report

Journal of Medical Case Reports
Background Primary aldosteronism screening indications include hypertension (resistant, severe, early onset, with stroke/other comorbidities/sleep apnea), hypokalemia, adrenal incidentaloma, and primary aldosteronism first-degree relatives.
Yug Garg, Madhumati S. Vaishnav, Reshma Harsha, Nidhi Garg, Siddhartha Dinesha, Leena Lekkala, Thummala Kamala, Kavitha Muniraj, Sathyanarayana Srikanta, Samatvam Endocrinology Diabetes Collaborative Group   +9 more
doaj   +1 more source

Clinical significance of CYP11B2 immunostaining in unilateral primary aldosteronism

Endocrine Connections
Objective: The associations between adrenal histopathology, lateralization studies, and surgical outcomes in primary aldosteronism remain poorly characterized.
Marianna Viukari, Helena Leijon, Tiina Vesterinen, Sanni Söderlund, Päivi Hämäläinen, Iina Yliaska, Päivi Rautiainen, Reeta Rintamäki, Minna Soinio, Ilkka Pörsti, Pasi I Nevalainen, Niina Matikainen   +11 more
doaj   +1 more source