Results 71 to 80 of about 4,504,450 (222)

A Patient with Concurrent Primary Aldosteronism and Page Kidney

, 2011
The ratio of aldosterone-to-renin activity is currently recommended as a screening test for primary aldosteronism ( PA). There are many factors interfering the interpretation of aldosterone-renin ratio (ARR) and could hamper in-time diagnosis of PA. Here,
郭錦輯;徐煥倫;黃昭淵;劉高郎;吳允升;蔡靜瑋;王偉傑, KUO, CHIN-CHI;HSU, HUAN-LUN;HUANG, CHAO-YUAN;LIU, KAO-LANG;WU, VIN-CENT;TSAI, CHING-WEI;WANG, WEI-JIE   +1 more
core   +1 more source

Use of Steroid Profiling Combined With Machine Learning for Identification and Subtype Classification in Primary Aldosteronism [PDF]

, 2020
Importance Most patients with primary aldosteronism, a major cause of secondary hypertension, are not identified or appropriately treated because of difficulties in diagnosis and subtype classification. Applications of artificial intelligence combined
Lenders, Jacques W. M., Eisenhofer, Graeme, Beuschlein, F., Burrello, J., Januszewicz, Andrzej, Mulatero, P., Peitzsch, M., Cannistraci, Carlo Vittorio, Buffolo, Fabrizio, Januszewicz, A., Durán, Claudio, Burrello, Jacopo, Riester, Anna, Cannistraci, Carlo, Williams, Tracy Ann, Peitzsch, Mirko, Williams, T. A., Prejbisz, A., Williams, T.A., Buffolo, F., Mulatero, Paolo, Reincke, M., Cannistraci, C.V., Prejbisz, Aleksander, Beuschlein, Felix, Riester, A., Lenders, J.W.M., Eisenhofer, G., Lenders, Jacques W M, Reincke, Martin, Durán, C.   +30 more
core   +1 more source

Advances in the biochemical diagnostics of primary aldosteronism: from immunoassays to steroidomics and proteomics

Frontiers in Endocrinology
Primary aldosteronism is the most common cause of secondary hypertension, yet most cases remain unrecognized and left without optimal treatment. The diagnostic inertia may be attributed to the lack of specific symptoms, insufficient awareness among ...
Alicja Szatko, Alicja Szatko, Alicja Szatko, Agata Toboła, Henrik Falhammar, Henrik Falhammar, Wojciech Zgliczyński, Piotr Glinicki, Piotr Glinicki   +8 more
doaj   +1 more source

HCG-responsive aldosteronoma with transient secretion during pregnancy confirmed through HCG-stimulated adrenal venous sampling

Frontiers in Endocrinology, 2023
Primary aldosteronism can be regulated by the ectopic expression of G-protein coupled receptors in aldosteronomas or bilateral hyperplasias. We report a rare case of a young woman in whom 2 pregnancies were complicated by pre-eclampsia and 1 miscarriage.
Frederic Castinetti, Carole Guerin, Estelle Louiset, André Lacroix   +3 more
doaj   +1 more source

A Giant 5000 g Primary Adrenocortical Carcinoma: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Adrenocortical carcinoma (ACC) is an aggressive malignancy that may present without hormonal symptoms. A 64 years old woman with abdominal pain, weight loss, and anemia had a massive adrenal tumor that required complex surgery. ACC should be considered in large abdominal masses. Complete surgical resection is essential.
Sadin Zahra, Aghajanzadeh Manouchehr, Mohammad Reza Sadin, Dadashi Arsalan, Poorsafar Mahdi, Aghzadeh Zeynab, Khyabani Mahmood, Shafaghi Afshin   +7 more
wiley   +1 more source

Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1‐Dependent Suppression of ROMK

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT Aim Hyperkalemia is prevalent in the elderly, and underlying molecular mechanisms remain incompletely understood. We hypothesized that Klotho deficiency, a feature of aging, impairs renal potassium homeostasis and contributes to hyperkalemia. Methods Klotho heterozygous knockout (KLhet) mice, characterized by reduced Klotho levels, were used ...
Wakako Kawarazaki, Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Takeshi Marumo, Toshiro Fujita   +6 more
wiley   +1 more source

A Ten Year Overview of Adrenal Vein Sampling in Croatia: Insights and Outcomes

Clinical Endocrinology, Volume 105, Issue 5, Page 533-539, November 2026.
ABSTRACT Background Adrenal vein sampling (AVS) is the gold standard for subtype differentiation in primary aldosteronism (PA), yet it remains technically demanding and resource intensive. However, data on long‐term performance, learning curves, and concordance with imaging in real‐world clinical practice are limited.
Karin Zibar Tomsic, Ana Marija Alduk, Elvira Kresic, Ivana Kraljevic, Darko Kastelan   +4 more
wiley   +1 more source

Primary aldosteronism with hypokalemic rhabdomyolysis: a case report and review of the literature

Journal of Medical Case Reports
Background Hypokalemic rhabdomyolysis is a rare clinical manifestation of primary aldosteronism, making its diagnosis challenging, particularly when it becomes the primary presenting symptom.
Pingan Shi, Chao Wang, Yuanjun Lyu
doaj   +1 more source

Unmasking Hormonal Mechanisms of Hypertension in Obesity

JACC: Basic to Translational Science
Summary: Understanding hormonal mechanisms of obesity-related hypertension may inform targeted therapy. Participants with obesity and hypertension underwent deep-phenotyping procedures to detect the primary aldosteronism phenotype, low-renin phenotype ...
Stéfanie Parisien-La Salle, MD, Cheng-Hsuan Tsai, MD, Andrew J. Newman, MD, Justin M. Chan, MD, Julia Milks, MD, Gail Adler, MD, PhD, Arnaldo Ferrebus, BA, Isabelle Hanna, BA, Sanan Mahrokhian, BA, Bertram Pitt, MD, Jenifer M. Brown, MD, Anand Vaidya, MD   +11 more
doaj   +1 more source

Primary Aldosteronism and Pregnancy

Kidney & Blood Pressure Research, 2020
Objective: Primary aldosteronism (PA) may present at younger age and may thus complicate pregnancy. Our aim was to identify female patients in whom PA was diagnosed after pregnancy complicated with hypertension and to analyze possible hypertension ...
Tomáš Zelinka, Ondřej Petrák, Ján Rosa, Robert Holaj, Branislav Štrauch, Jiří Widimský Jr.   +5 more
doaj   +1 more source