Results 71 to 80 of about 5,663,878 (222)
Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5463-5475, July 2026.ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler +4 more
wiley +1 more source
Contrast-enhanced MRI index of diffuse myocardial fibrosis is increased in primary aldosteronism
, 2014 Purpose: To assess the degree of myocardial fibrosis in patients with primary aldosteronism (PA). Materials and Methods: Twenty-five patients with PA and 12 age-matched healthy volunteers underwent cine and late gadolinium enhancement (LGE) magnetic ...
曾文毅 ;林亮宇 ;虞希禹 ;蘇茂源 ;吳允升 ;吳寬墩 ;闕士傑 ;劉高郎 ;王碩盟 ;林彥宏 +1 more
core +1 more source
Advanced Science, Volume 13, Issue 32, 9 June 2026.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Analytical Science Advances, Volume 7, Issue 1, June 2026.ABSTRACT Steroids are critical for numerous physiological processes; disruption in their metabolism is associated with numerous endocrine disorders. Steroid quantification is essential to improve the understanding and diagnosis of these pathologies. Historically, urinary steroid profiling has been performed using low‐throughput gas chromatography mass ...
Joshua T. Bain +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
, 2017 Objectives: To develop algorithms of locating patients with primary aldosteronism (PA) using insurance reimbursement data and to validate the algorithms using medical charts.
楊為舜;林彥宏;楊偉勛;吳允升;吳寬墩 +1 more
core +1 more source
Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Aims The epithelial sodium channel ENaC consists of the subunits α, β, and γ and is activated at an individual channel level by proteolytic processing. Murine γENaC contains a distal polybasic tract 186RKRK mediating proteolytic ENaC activation by serine proteases in vitro.
Daniel Essigke +8 more
wiley +1 more source
Update in Primary Aldosteronism [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2009 Primary aldosteronism (PA) is a condition well worth detecting because it is a common cause of hypertension and is associated with excessive morbidity for the degree of hypertension and reduced quality of life, all of which can be abrogated with specific surgical or medical treatment.
openaire +10 more sources
The Journal of Clinical Hypertension, Volume 28, Issue 6, June 2026.ABSTRACT Carotid–femoral pulse‐wave velocity (cfPWV) is a marker of central arterial stiffness and an established predictor of cardiovascular risk in hypertension. Although elevated lipoprotein(a) [Lp(a)] concentrations and peripheral arterial disease (PAD) are associated with atherosclerotic cardiovascular disease, their independent associations with ...
Bibombe P. Mwipatayi +8 more
wiley +1 more source
Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.Sex‐specific 24‐hour minimum heart rate (MHR) stratification in patients with type 2 diabetes mellitus and essential hypertension (T2DM‐EH). Three key findings are shown from subgroup analysis: (1) In the normal MHR group (Group B), advancing age independently predicts reduced deceleration capacity (DC) in both sexes.
Pingping Wu +6 more
wiley +1 more source