Results 51 to 60 of about 5,663,878 (222)

Comparative Genomics and Transcriptome Profiling in Primary Aldosteronism [PDF]

, 2018
Primary aldosteronism is the most common form of endocrine hypertension with a prevalence of 6% in the general population with hypertension. The genetic basis of the four familial forms of primary aldosteronism (familial hyperaldosteronism FH types I-IV)
Williams, T. A., Aristizabal Prada, Elke Tatjana, Tetti, M., Lucie Meyer, Eva Sušnik, Williams, Tracy A., Meyer, Lucie S., Isabella Castellano, Williams, Tracy A, Yang, Yuhong, Castellano, I., Martina Tetti, Yang, Y., Tracy Williams, Beuschlein, Felix, Felix Beuschlein, Tetti, Martina, Martin Reincke, Yuhong Yang, Meyer, Lucie S, Sušnik, Eva, Castellano, Isabella, Reincke, Martin, Elke Aristizabal Prada   +23 more
core   +1 more source

Diverse Responses of Autoantibodies to the Angiotensin II Type 1 Receptor in Primary Aldosteronism [PDF]

, 2019
Primary aldosteronism is a common form of endocrine hypertension mainly caused by a unilateral aldosterone-producing adenoma (APA) or bilateral adrenal hyperplasia (BAH).
Nirschl, Nina, Williams, T. A., Bidlingmaier, Martin, Burrello, J., Philippe, Aurélie, Yang, Yuhong, Hübener, Christoph, Rank, Petra, Beuschlein, Felix, Burrello, Jacopo, Sturm, Lisa, Jaquin, Diana, Williams, Tracy Ann, Dragun, Duska, Reincke, Martin   +14 more
core   +1 more source

Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis.

Journal of Clinical Endocrinology and Metabolism, 2021
CONTEXT The aldosterone-to-renin ratio (ARR) is the guideline-recommended screening test for primary aldosteronism. However, there is limited data in regard to the diagnostic performance of the ARR. OBJECTIVE To evaluate the sensitivity and specificity
A. Hung, Sumaiya Ahmed, Ankur Gupta, A. Davis, G. Kline, A. Leung, M. Ruzicka, S. Hiremath, G. Hundemer   +8 more
semanticscholar   +1 more source

The Saline Infusion Test for Primary Aldosteronism: Implications of Immunoassay Inaccuracy

Journal of Clinical Endocrinology and Metabolism, 2021
Context Diagnosis of primary aldosteronism (PA) for many patients depends on positive results for the saline infusion test (SIT). Plasma aldosterone is often measured by immunoassays, which can return inaccurate results.
G. Eisenhofer, Max Kurlbaum, M. Peitzsch, G. Constantinescu, H. Remde, M. Schulze, Denise Kaden, L. Müller, C. Fuss, S. Kunz, S. Kolodziejczyk-kruk, Sven Gruber, A. Prejbisz, F. Beuschlein, T. Williams, M. Reincke, J. Lenders, M. Bidlingmaier   +17 more
semanticscholar   +1 more source

Primary Aldosteronism, Aldosterone, and Extracellular Vesicles

Endocrinology, 2021
Abstract Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone concentration. Recently, a broad spectrum of PA has been recognized, which brings new challenges associated with early identification of this condition that affect renal epithelial
Cristian A Carvajal, Alejandra Tapia-Castillo, Jorge A Pérez, Carlos E Fardella   +3 more
openaire   +2 more sources

Aldosterone, Renin and ARR Variability in Screening for Primary Aldosteronism.

Journal of Clinical Endocrinology and Metabolism, 2022
CONTEXT The plasma aldosterone concentration (PAC), renin and aldosterone-renin ratio (ARR) are used to screen for primary aldosteronism (PA). Substantial intra-individual variability of PAC and ARR using plasma renin activity in the context of usual ...
Elisabeth Ng, S. Gwini, Renata Libianto, K. Choy, Z. Lu, Jimmy Shen, J. Doery, P. Fuller, Jun Yang   +8 more
semanticscholar   +1 more source

A Patient with Concurrent Primary Aldosteronism and Page Kidney

, 2011
The ratio of aldosterone-to-renin activity is currently recommended as a screening test for primary aldosteronism ( PA). There are many factors interfering the interpretation of aldosterone-renin ratio (ARR) and could hamper in-time diagnosis of PA. Here,
郭錦輯;徐煥倫;黃昭淵;劉高郎;吳允升;蔡靜瑋;王偉傑, KUO, CHIN-CHI;HSU, HUAN-LUN;HUANG, CHAO-YUAN;LIU, KAO-LANG;WU, VIN-CENT;TSAI, CHING-WEI;WANG, WEI-JIE   +1 more
core   +1 more source

Primary Aldosteronism and the Role of Mineralocorticoid Receptor Antagonists for the Heart and Kidney

Annual Review of Medicine, 2022
Primary aldosteronism is the most common cause of secondary hypertension but is frequently underrecognized and undertreated. Moreover, patients with primary aldosteronism are at a markedly increased risk for target organ damage to the heart and kidney ...
Jordana B. Cohen, I. Bancos, Jenifer M. Brown, Harini Sarathy, Adina F. Turcu, D. Cohen   +5 more
semanticscholar   +1 more source

Delayed diagnosis of primary aldosteronism in patients with autosomal dominant polycystic kidney diseases

, 2014
Hypertension is a frequent early manifestation of autosomal dominant polycystic kidney disease (ADPKD). Several mechanisms can cause hypertension in ADPKD patients, although, primary aldosteronism (PA) as a possible manifestation of hypertension in ADPKD
Kao, Chih-Chin;Wu, Vin-Cent;Kuo, Chin-Chi;Lin, Yen-Hung;Hu, Ya-Hui;Tsai, Yao-Chou;Wu, Che-Hsiung;Wu, Kwan-Dun, 郭錦輯 ;吳允升 ;吳寬墩 ;林彥宏   +1 more
core   +1 more source

11C-Metomidate PET-CT versus adrenal vein sampling to subtype primary aldosteronism: a prospective clinical trial

Journal of Hypertension, 2022
Objective: Adrenal vein sampling (AVS) is recommended to subtype primary aldosteronism, but it is technically challenging. We compared 11C-Metomidate-PET-computed tomography (PET-CT) and AVS for subtyping of primary aldosteronism.
T. Puar, C. Khoo, C. Tan, A. Tong, Michael Chien Sheng Tan, A. E. Teo, K. Ng, Kang Min Wong, A. Reilhac, J. O’Doherty, C. Gomez-Sanchez, P. Kek, S. Yee, A. Tan, M. Chuah, Daphne Hui Min Lee, K. W. Wang, C. Zheng, Luming Shi, E. Robins, Roger S Foo   +20 more
semanticscholar   +1 more source