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Primary Aldosteronism☆ [PDF]

Hypertension, 2014
See related article, p 783–789 Primary aldosteronism (PA) is the most common form of secondary hypertension accounting for ≈10% of patients referred to hypertension clinics and as high as 20% of those with refractory hypertension.1 The most important causes of PA are idiopathic hyperaldosteronism (IHA), also called bilateral zona glomerulosa ...
openaire   +5 more sources

Disordered CYP11B2 Expression in Primary Aldosteronism [PDF]

, 2017
Primary aldosteronism is the most common type of secondary hypertension affecting 6-10% of patients with primary hypertension. PA is mainly caused by unilateral hyperaldosteronism due to an aldosterone-producing adenoma, unilateral hyperplasia with or ...
Maniselvan Kuppusamy, Tracy Williams, Williams, T. A., Kuppusamy, Maniselvan, Martin Reincke, Gomez-Sanchez, Celso E., Williams, Tracy Ann, Celso Gomez-Sanchez, Reincke, Martin   +8 more
core   +1 more source

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

Journal of Diabetes Investigation, 2020
Aims/Introduction An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear.
Mikiko Okazaki‐Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, Hitoshi Sugihara   +5 more
doaj   +1 more source

Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism

Diagnostics, 2022
Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate
Yilin Chen, Tingyan Xu, Jianzhong Xu, Limin Zhu, Dian Wang, Yan Li, Jiguang Wang   +6 more
doaj   +1 more source

Primary Aldosteronism or Not Primary Aldosteronism [PDF]

Hypertension, 2017
See related article, pp 950–956 Primary aldosteronism (PA) within hypertensive populations is no longer regarded as being a rare phenomenon. Although some debate around its overall frequency remains, one of the most robust studies in recent years describes a prevalence of ≈10% in unselected hypertensives1; this may rise to ≤20% in subjects with ...
openaire   +2 more sources

THERAPY OF ENDOCRINE DISEASE: Medical treatment of primary aldosteronism [PDF]

, 2019
In patients with primary aldosteronism specific treatment provides prognostic benefit over optimal antihypertensive therapy and is therefore crucial to reduce mortality and morbidity in this subgroup of patients with hypertension.
Lechner, Benjamin, Beuschlein, Felix, Heinrich, Daniel A., Schneider, Holger, Heinrich, Daniel, Adolf, Christian, Holler, Finn, Lechner, Katharina, Reincke, Martin   +8 more
core   +1 more source

Adrenocortical Causes of Hypertension

International Journal of Hypertension, 2011
Primary aldosteronism is the most common cause of secondary hypertension. In the past, screening for primary aldosteronism was offered only in patients with hypertension associated with hypokalemia.
Andreas Moraitis, Constantine Stratakis
doaj   +1 more source

Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Primary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement.
Tomomi Ueda, Yuya Tsurutani, Jun Osada, Kosuke Inoue, Yoshitomo Hoshino, Masato Ono, Kazuki Nakai, Jun Saito, Kazuhiko Yumoto, Tetsuo Nishikawa   +9 more
doaj   +1 more source

Diagnosis and Treatment of Primary Aldosteronism in 2017: Did We Achieve Our Goals? [PDF]

, 2017
For many decades primary aldosteronism (PA) was dismissed as a rare endocrine condition, but is nowadays widely accepted as the most frequent endocrine cause of hypertension, largely due to the widespread use of the aldosterone-to-renin ratio as a ...
Tracy Ann Williams, Beuschlein, Felix, Felix Beuschlein, Martin Reincke, Beuschlein, Felix; https://orcid.org/, Williams, Tracy Ann, Reincke, Martin; https://orcid.org/, Williams, Tracy Ann; https://orcid.org/, Reincke, Martin   +8 more
core   +1 more source

Abnormality of Aldosterone and Cortisol Late Pathways in Glucocorticoid-Remediable Aldosteronism. [PDF]

, 1994
Patients with glucocorticoid-remediable aldosteronism (GRA) possess a chimeric gene resulting from fusion of the genes encoding steroid aldosterone synthase and 11 beta-hydroxylase.
Boscaro, Marco, Kuhnle, Ursula, KUHNLE U, Fallo, Francesco, Sonino, Nicoletta   +4 more
core   +1 more source