Results 21 to 30 of about 4,504,450 (222)

Markers of Kidney Tubular Function Deteriorate While Those of Kidney Tubule Health Improve in Primary Aldosteronism After Targeted Treatments

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Targeted treatment with mineralocorticoid receptor antagonists (MRAs) or adrenalectomy in patients with primary aldosteronism (PA) causes a decline in estimated glomerular filtration rate; however, the associated simultaneous changes in ...
Vin‐Cent Wu, Chieh‐Kai Chan, Jeff S. Chueh, Yung‐Ming Chen, Yen‐Hung Lin, Chin‐Chen Chang, Po‐Chih Lin, Shiu‐Dong Chung   +7 more
doaj   +1 more source

Benefits of Surgical Over Medical Treatment for Unilateral Primary Aldosteronism

Frontiers in Endocrinology, 2022
Primary aldosteronism is the most common and modifiable form of secondary hypertension. Left untreated, primary aldosteronism leads high rates of cardiovascular, metabolic, and kidney disease.
Sumaiya Ahmed, Gregory L. Hundemer
doaj   +1 more source

Cortisol Co-Secretion and Clinical Usefulness of ACTH Stimulation Test in Primary Aldosteronism: A Systematic Review and Biases in Epidemiological Studies

Frontiers in Endocrinology, 2021
The hypothalamus-pituitary-adrenal (HPA) axis plays an important role in primary aldosteronism. Aldosterone biosynthesis is regulated not only by angiotensin II in the renin-angiotensin-aldosterone system, but also by adrenocorticotropic hormone (ACTH ...
Kosuke Inoue, Kosuke Inoue, Takumi Kitamoto, Takumi Kitamoto, Yuya Tsurutani, Jun Saito, Masao Omura, Tetsuo Nishikawa   +7 more
doaj   +1 more source

Concurrence of overt Cushing’s syndrome and primary aldosteronism accompanied by aldosterone-producing cell cluster in adjacent adrenal cortex: case report

BMC Endocrine Disorders, 2021
Background Various adrenal disorders including primary aldosteronism and Cushing’s syndrome lead to the cause of hypertension. Although primary aldosteronism is sometimes complicated with preclinical Cushing’s syndrome, concurrence of overt Cushing’s ...
Yoshiro Fushimi, Fuminori Tatsumi, Junpei Sanada, Masashi Shimoda, Shinji Kamei, Shuhei Nakanishi, Kohei Kaku, Tomoatsu Mune, Hideaki Kaneto   +8 more
doaj   +1 more source

Primary Aldosteronism and Cardiovascular Events: It is time to take guideline recommendations seriously [PDF]

, 2018
It is nowadays widely accepted that primary aldosteronism is the most frequent cause of endocrine hypertension. Prevalence rates among patients with hypertension are 6% in the primary care setting and 11% in tertiary care referral centers (1).
Martin Reincke, Reincke, Martin
core   +1 more source

Disordered CYP11B2 Expression in Primary Aldosteronism [PDF]

, 2017
Primary aldosteronism is the most common type of secondary hypertension affecting 6-10% of patients with primary hypertension. PA is mainly caused by unilateral hyperaldosteronism due to an aldosterone-producing adenoma, unilateral hyperplasia with or ...
Maniselvan Kuppusamy, Tracy Williams, Williams, T. A., Kuppusamy, Maniselvan, Martin Reincke, Gomez-Sanchez, Celso E., Williams, Tracy Ann, Celso Gomez-Sanchez, Reincke, Martin   +8 more
core   +1 more source

Salt Appetite and its Effects on Cardiovascular Risk in Primary Aldosteronism [PDF]

, 2020
First described in 1955 by Jerome W. Conn, primary aldosteronism (PA) today is well established as a relevant cause of secondary hypertension and accounts for about 5–10 % of hypertensives.
Heinrich, Daniel A., Schneider, Holger, Handgriff, Laura, Adolf, Christian, Reincke, Martin   +4 more
core   +1 more source

Consensus on Clinical Application of the CXCR4-targeted Imaging in the Diagnosis of Primary Aldosteronism(2022)

Xiehe Yixue Zazhi, 2022
Subtype classification of primary aldosteronism is important but challenging. Increasing evidence has shown that 68Ga-Pentixafor PET/CT imaging which targets CXCR4 is beneficial to the subtype classification of primary aldosteronism.
Chinese Urological Doctor Association Adrenal Hypertension Surgery Collaborative Organization Adrenal Group, Chinese Society of Endocrinology PET group, Chinese Society of Nuclear Medicine   +2 more
doaj   +1 more source

Primary Aldosteronism☆ [PDF]

Hypertension, 2014
See related article, p 783–789 Primary aldosteronism (PA) is the most common form of secondary hypertension accounting for ≈10% of patients referred to hypertension clinics and as high as 20% of those with refractory hypertension.1 The most important causes of PA are idiopathic hyperaldosteronism (IHA), also called bilateral zona glomerulosa ...
openaire   +5 more sources

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

Journal of Diabetes Investigation, 2020
Aims/Introduction An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear.
Mikiko Okazaki‐Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, Hitoshi Sugihara   +5 more
doaj   +1 more source