Results 11 to 20 of about 5,663,878 (222)

International histopathology consensus for unilateral primary aldosteronism [PDF]

open access: yesJournal of Clinical Endocrinology and Metabolism, 2021
Objective: Develop a consensus for the nomenclature and definition of adrenal histopathologic features in unilateral primary aldosteronism (PA). Context: Unilateral PA is the most common surgically treated form of hypertension. Morphologic examination
Lenders, Jacques W. M.   +20 more
core   +3 more sources

Primary Aldosteronism

open access: yesGland Surgery, 2020
Primary aldosteronism remains a leading cause of secondary hypertension, and its diagnosis and management continue to pose a challenge for clinicians.
Pillai, Padma Raghavan   +7 more
core   +4 more sources

Single-Center Prospective Cohort Study on the Histopathology, Genotype, and Postsurgical Outcomes of Patients With Primary Aldosteronism [PDF]

open access: yesHYPERTENSION, 2021
Unilateral forms of primary aldosteronism are usually surgically treated to remove the source of aldosterone excess. After adrenalectomy, aldosteronism persists in some patients indicating abnormal aldosterone production from the unresected gland.
Bidlingmaier, Martin   +11 more
core   +2 more sources

Identification of risk loci for primary aldosteronism in genome-wide association studies. [PDF]

open access: yesNature Communications, 2022
Primary aldosteronism affects up to 10% of hypertensive patients and is responsible for treatment resistance and increased cardiovascular risk. Here we perform a genome-wide association study in a discovery cohort of 562 cases and 950 controls and ...
Rossi, G.P.   +71 more
core   +2 more sources

Subclinical primary aldosteronism. [PDF]

open access: yesArch Endocrinol Metab
Primary aldosteronism (PA) is a major contributor to hypertension and cardiovascular disease. Subclinical PA, a preclinical or early manifestation of PA, has been identified in individuals with normal blood pressure and in those with mild hypertension without signs or symptoms of overt PA, using evidence from histopathology, hormonal biochemistry ...
Parisien-La Salle S   +4 more
europepmc   +5 more sources

Adiponectin and Insulin Sensitivity in Primary Aldosteronism [PDF]

open access: yesAmerican Journal of Hypertension, 2007
BACKGROUND: A high prevalence of metabolic syndrome has been reported in primary aldosteronism. Low levels of adiponectin, an adipokine with insulin-sensitizing properties, are considered a hallmark of the metabolic syndrome.
Francesco Fallo   +2 more
exaly   +1 more source

Primary aldosteronism and pregnancy

open access: yesPregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2015
Primary aldosteronism is the most common cause of secondary hypertension. Less than 50 cases of pregnancy in women with primary aldosteronism have been reported, suggesting the disorder is significantly underdiagnosed in confinement.
Morton, Adam
core   +6 more sources

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

open access: yesNature Medicine, 2023
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery.
W. X   +41 more
semanticscholar   +1 more source

Accuracy of Gallium-68 Pentixafor Positron Emission Tomography–Computed Tomography for Subtyping Diagnosis of Primary Aldosteronism

open access: yesJAMA Network Open, 2023
This diagnostic study investigates the accuracy of gallium-68 pentixafor positron emission tomography–computed tomography vs adrenal vein sampling in subtyping diagnosis of primary aldosteronism.
Jinbo Hu   +19 more
semanticscholar   +1 more source

The Value of Targeting CXCR4 with 68Ga-Pentixafor PET/CT for Subtyping Primary Aldosteronism.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2023
PURPOSE Primary aldosteronism (PA) is one of the leading causes of secondary hypertension, and its diagnostic subtyping consistently presents a clinical challenge.
Yanqing Zheng   +17 more
semanticscholar   +1 more source

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