Gland Surgery, 2020 Primary aldosteronism remains a leading cause of secondary hypertension, and its diagnosis and management continue to pose a challenge for clinicians.
Pillai, Padma Raghavan +7 more
core +6 more sources
PRIMARY ALDOSTERONISM: CURRENT DIAGNOSTIC APPROACH
Байкальский медицинский журнал, 2022 Primary aldosteronism is characterized by aldosterone secretion that is independent of renin and angiotensin II. The deleterious effects of primary aldosteronism are mediated by excessive activation of the mineralocorticoid receptor that results in the ...
Elena S. Eniseeva
doaj +2 more sources
Bilateral superselective adrenal artery embolization for primary aldosteronism: A comparative evaluation of clinical efficacy and safety [PDF]
Journal of International Medical ResearchObjective Superselective adrenal arterial embolization with ethanol has demonstrated promising efficacy in patients with primary aldosteronism and lateralized aldosterone secretion.
Dongliang Cao +5 more
doaj +2 more sources
Subclinical primary aldosteronism: toward a conceptual framework linking primary aldosteronism and low-renin hypertension [PDF]
Frontiers in EndocrinologyPrimary aldosteronism (PA) has traditionally been considered a rare cause of secondary hypertension, but growing evidence supports a broader continuum of renin-independent aldosterone production extending into normotensive and mildly hypertensive ...
Chan Ho Park
doaj +2 more sources
Subclinical primary aldosteronism [PDF]
Archives of Endocrinology and MetabolismPrimary aldosteronism (PA) is a major contributor to hypertension and cardiovascular disease. Subclinical PA, a preclinical or early manifestation of PA, has been identified in individuals with normal blood pressure and in those with mild hypertension ...
Stéfanie Parisien-La Salle +4 more
doaj +2 more sources
Clinical significance of CYP11B2 immunostaining in unilateral primary aldosteronism [PDF]
Endocrine ConnectionsObjective: The associations between adrenal histopathology, lateralization studies, and surgical outcomes in primary aldosteronism remain poorly characterized.
Marianna Viukari +11 more
doaj +2 more sources
International histopathology consensus for unilateral primary aldosteronism [PDF]
, 2021 Objective: Develop a consensus for the nomenclature and definition of adrenal histopathologic features in unilateral primary aldosteronism (PA). Context: Unilateral PA is the most common surgically treated form of hypertension. Morphologic examination
Lenders, Jacques W. M. +20 more
core +2 more sources
Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism [PDF]
, 2020 Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT1R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in
Siyuan, Gong +3 more
core +3 more sources
Single-Center Prospective Cohort Study on the Histopathology, Genotype, and Postsurgical Outcomes of Patients With Primary Aldosteronism [PDF]
, 2021 Unilateral forms of primary aldosteronism are usually surgically treated to remove the source of aldosterone excess. After adrenalectomy, aldosteronism persists in some patients indicating abnormal aldosterone production from the unresected gland.
Bidlingmaier, Martin +23 more
core +1 more source
Mutation in Aldosterone Producing Adenoma [PDF]
Endocrinology and Metabolism, 2017 Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described and discussed in
Jian-Jhong Wang +4 more
doaj +1 more source