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Primary Aldosteronism☆ [PDF]

Hypertension, 2014
See related article, p 783–789 Primary aldosteronism (PA) is the most common form of secondary hypertension accounting for ≈10% of patients referred to hypertension clinics and as high as 20% of those with refractory hypertension.1 The most important causes of PA are idiopathic hyperaldosteronism (IHA), also called bilateral zona glomerulosa ...
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Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

Journal of Diabetes Investigation, 2020
Aims/Introduction An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear.
Mikiko Okazaki‐Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, Hitoshi Sugihara   +5 more
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Identification of risk loci for primary aldosteronism in genome-wide association studies

Nature Communications, 2022
Detection of primary aldosteronism, the most common form of secondary arterial hypertension, is essential for targeted management and prevention of cardiovascular complications.
Edith Le Floch, Teresa Cosentino, Casper K. Larsen, Felix Beuschlein, Martin Reincke, Laurence Amar, Gian-Paolo Rossi, Kelly De Sousa, Stéphanie Baron, Sophie Chantalat, Benjamin Saintpierre, Livia Lenzini, Arthur Frouin, Isabelle Giscos-Douriez, Matthis Ferey, Alaa B. Abdellatif, Tchao Meatchi, Jean-Philippe Empana, Xavier Jouven, Christian Gieger, Melanie Waldenberger, Annette Peters, Daniele Cusi, Erika Salvi, Pierre Meneton, Mathilde Touvier, Mélanie Deschasaux, Nathalie Druesne-Pecollo, Sheerazed Boulkroun, Fabio L. Fernandes-Rosa, Jean-François Deleuze, Xavier Jeunemaitre, Maria-Christina Zennaro   +32 more
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Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism

Diagnostics, 2022
Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate
Yilin Chen, Tingyan Xu, Jianzhong Xu, Limin Zhu, Dian Wang, Yan Li, Jiguang Wang   +6 more
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Primary Aldosteronism or Not Primary Aldosteronism [PDF]

Hypertension, 2017
See related article, pp 950–956 Primary aldosteronism (PA) within hypertensive populations is no longer regarded as being a rare phenomenon. Although some debate around its overall frequency remains, one of the most robust studies in recent years describes a prevalence of ≈10% in unselected hypertensives1; this may rise to ≤20% in subjects with ...
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Adrenocortical Causes of Hypertension

International Journal of Hypertension, 2011
Primary aldosteronism is the most common cause of secondary hypertension. In the past, screening for primary aldosteronism was offered only in patients with hypertension associated with hypokalemia.
Andreas Moraitis, Constantine Stratakis
doaj   +1 more source

Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Primary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement.
Tomomi Ueda, Yuya Tsurutani, Jun Osada, Kosuke Inoue, Yoshitomo Hoshino, Masato Ono, Kazuki Nakai, Jun Saito, Kazuhiko Yumoto, Tetsuo Nishikawa   +9 more
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Primary aldosteronism: Pathophysiological mechanisms of cell death and proliferation

Frontiers in Endocrinology, 2022
Primary aldosteronism is the most common surgically curable form of hypertension. The sporadic forms of the disorder are usually caused by aldosterone overproduction from a unilateral adrenocortical aldosterone-producing adenoma or from bilateral ...
Martina Tetti, Martina Tetti, Siyuan Gong, Franco Veglio, Martin Reincke, Tracy Ann Williams, Tracy Ann Williams   +6 more
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Masked arterial hypertension in a 64-year-old man with primary aldosteronism

Blood Pressure, 2022
Purpose Primary aldosteronism is one of the most frequent causes of secondary arterial hypertension, and whether primary aldosteronism is associated with masked hypertension is unknown.
Joanna Kanarek-Kucner, Beata Graff, Vlasta Bari, Rufus Barraclough, Krzysztof Narkiewicz, Michał Hoffmann   +5 more
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Unusual presentation of primary aldosteronism with advanced target organ damage: A case report

Radiology Case Reports, 2019
Patients with primary aldosteronism have greater cardiovascular morbidity and mortality than patients with primary hypertension and a comparable cardiovascular risk profile.
Cristiano Fava, MD, PhD, Filippo Cattazzo, MD, Riccardo Bernasconi, MD, Simone Romano, MD, Pietro Minuz, MD   +4 more
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