Results 41 to 50 of about 66,403 (259)

School bullying and social-emotional competence: the mediating role of teacher-student relationships

open access: yesFrontiers in Psychology
ObjectiveTo investigate how both school bullying and victimization affects social–emotional competence among Chinese preadolescents and early adolescents, with a specific focus on the potential mediating effect of teacher-student relationships.MethodsThe
Li Shengxing   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Une expérience pédagogique musicale en Grande Section Maternelle et Cours Préparatoire

open access: yesRecherches en Éducation, 2013
During a learning experience which took place first in a nursery, and then in a primary school, pupils have composed their own pieces of music. We are asking about the nature of the processes used. According to Vygotsky, culture is considered as the core
Marie-Renée Guilloret
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

ANALISIS KEBUTUHAN MAHASISWA PROGRAM STUDI PGSD UAD DALAM MATA KULIAH PEMBELAJARAN TERPADU DI SEKOLAH DASAR

open access: yesProfesi Pendidikan Dasar, 2018
Good mastery of integrated learning model is one of important competencies for primary school education students. Without good mastery, they will find it hard to design and do instruction in primary schools that involve a number of fields of study and ...
Amaliyah Ulfah
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Climats et pratiques de leadership dans les équipes enseignantes des écoles élémentaires

open access: yesRecherches en Éducation, 2013
The idea that the climate of the French primary schools must be carefully examined after the last publication of inquiries PISA, is henceforth imperative.
Joël Rich
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy