Results 61 to 70 of about 66,403 (259)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Corrigendum: Measuring adaptive teaching in classroom discourse: Effects on student learning in elementary science education

Frontiers in Education, 2023
Ilonca Hardy, Nicola Meschede, Susanne Mannel   +2 more
doaj   +1 more source

Comment traiter des religions au primaire dans un contexte laïque : finalités, difficultés, contradictions ?

Recherches en Éducation
In Geneva's elementary school, religious facts take up a lot of space. As Geneva is a secular Swiss canton, this subject is integrated into the history teaching and must be approached from a scientific perspective.
Valérie Opériol
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Philosopher avec les enfants dès l’école élémentaire grâce à la littérature : analyse d’un corpus de trois années d’ateliers de philosophie en cycle 3

Recherches en Éducation, 2012
Raising philosophical issues is not an adult's prerogative. At a very young age, children wondering at the world around them start asking questions about life, death and human relations. To use G.
Edwige Chirouter
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Du primaire au second degré : les changements dans les

Recherches en Éducation
The upper primary schools of the Third Republic were the key establishments in the development of extended schooling. Created in the 1880s, they evolved a lot until their transformation into a middle school in 1941.
Amandine Charvet
doaj   +1 more source

The Effectiveness of Preschool Education on Social Adjustment of Elementary Students

Indigenous, 2018
Considering the physical, psychological and social preparation of the child in pre-primary school for advancement in various aspects of development and the certificate of various researches, the positive effect of this course's education on the social ...
Mohammad Tahan, Masume Kalantari
doaj   +1 more source