Results 51 to 60 of about 66,403 (259)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Recherches en ÉducationThe introduction of the Plan d'Etudes Romand for primary schools in French-speaking Switzerland in 2012 has given geography teaching a new framework and new directions.
Sylvie Joublot Ferré
doaj +1 more source
Leadership distribué, leadership partagé : coopération et pouvoir
Recherches en Éducation, 2013 In France, a lot of research has documented the role of “principals” in the secondary school. Within the framework of a study carried out in LACES (EA 4140), the author investigates the mechanisms of teamwork in six primary schools through questionnaires
Serge Le Bihan
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Factors influencing AI adoption by Chinese mathematics teachers in STEM education
Scientific ReportsThis study refines the Extended Unified Theory of Acceptance and Use of Technology (UTAUT2) to explore the factors influencing the adoption and utilization of artificial intelligence (AI) by Chinese mathematics teachers in STEM education, aiming to ...
Wen Du +4 more
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Recherches en ÉducationThe introduction of a new syllabus for primary and elementary education in Switzerland's French-speaking cantons in 2011 presented a challenge for all those involved in the education system, especially teachers and trainers. Indeed, the implementation of
Sylvie Joublot Ferré
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Initier des élèves de 4-5 ans à la géographie : enjeux et défis
Recherches en ÉducationThis article looks at the issues involved in teaching geography in Cycle 1 and the results of collaborative research into teaching practices. In French-speaking Switzerland, geography teaching underwent major shifts with the introduction of the Plan d ...
Alain Pache +2 more
doaj +1 more source