Results 171 to 180 of about 95,754 (365)

Prognostic scores in primary biliary cholangitis

Future Science OA
Aim: Evaluating prognostic scores' utility in predicting ursodeoxycholic acid (UDCA) biochemical response (BR) and long-term liver-related complications in primary biliary cholangitis (PBC) patients.
Ramzi Tababi, Soumaya Mrabet, Imen Akkari, Raida Harbi, Elhem Ben Jazia   +4 more
doaj   +1 more source

Giant Splenorenal Shunt in a Young Patient with Autoimmune Hepatitis/Primary Biliary Cholangitis Overlap Syndrome and Portal Vein Thrombosis [PDF]

, 2017
Fabrizio Chegai, Armando Ugo Cavallo, Marco Forcina, V. Giuricin, Francesca Castellani, Laura Greco, Matteo Manuelli, Tommaso Maria Manzia, Gianluigi Sergiacomi   +8 more
openalex   +1 more source

Potential Role of Inflammation-Promoting Biliary Microbiome in Primary Sclerosing Cholangitis and Cholangiocarcinoma [PDF]

, 2022
Katsuyuki Miyabe, Vinay Chandrasekhara, Nicha Wongjarupong, Jun Chen, Lu Yang, Stephen Johnson, Nicholas Chia, Marina Walther-António, Janet Yao, Sean C. Harrington, Cynthia K. Nordyke, John E. Eaton, Andrea A. Gossard, Sharad Oli, Hamdi A. Ali, Sravanthi Lavu, Nasra H. Giama, Fatima Hassan, Hawa M. Ali, Felicity Enders, Sumera I. Ilyas, Gregory J. Gores, Mark Topazian, Purna Kashyap, Lewis R. Roberts   +24 more
openalex   +1 more source

Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response

The FEBS Journal, EarlyView.
Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo, Juan García‐Sáez, María Figueroa‐Fuentes, Annalisa Addante, Cesáreo Roncero, Nerea Lazcanoiturburu, Beatriz Pacheco, Julián Sanz, Cristina Gato, Eva Fernández‐Calderón, María de la O López, Águeda González‐Rodríguez, Almudena Porras, Flavio Maina, Isabel Fabregat, Blanca Herrera, Aránzazu Sánchez   +16 more
wiley   +1 more source

Clinical Outcomes and Validation of Ursodeoxycholic Acid Response Scores in Patients with Korean Primary Biliary Cholangitis: A Multicenter Cohort Study

, 2023
Jong-In Chang, Jung Hee Kim, Dong Hyun Sinn, Ju‐Yeon Cho, Kwang Min Kim, Joo Hyun Oh, Yewan Park, Won Sohn, Myung Ji Goh, Wonseok Kang, Geum‐Youn Gwak, Yong‐Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik   +15 more
openalex   +2 more sources

Steatotic Liver Disease: A Key Related Risk Factor in the Emergence of Metabolic Syndrome‐Related Disorders

Hepatology Research, EarlyView.
It is speculated that the onset of obesity‐related diseases follows the sequence of obesity → SLD → MetS‐related diseases. In this study, the contribution of SLD to each MetS‐related disease was large for T2D and hypertension and SLD contributed to the onset and new onset of the disease by the 7‐year follow‐up.
Yoshihiro Kamada, Makoto Fujii, Hitoshi Nishizawa, Shiro Fukuda, Makoto Yamada, Iichiro Shimomura, Eiji Miyoshi   +6 more
wiley   +1 more source

The Hepatic Steatosis Diagnostic Performance Using Attenuation Imaging With the Magnetic Resonance Imaging‐Based Proton Density Fat Fraction as the Reference Standard: A Large, Prospective, Multicenter Cohort Study in Japan

Hepatology Research, EarlyView.
In a multicenter cohort of 1059 patients, attenuation imaging (ATI) showed good diagnostic performance and strong correlation with MRI‐PDFF, supporting its value as a noninvasive method for evaluating hepatic steatosis. ABSTRACT Background Attenuation imaging (ATI) is used for the noninvasive diagnosis of hepatic steatosis (HS) based on the ultrasound ...
Takashi Nishimura, Hiroko Iijima, Yasuaki Suzuki, Kent Imajo, Tamami Abe, Hidekatsu Kuroda, Masashi Hirooka, Asako Nogami, Sadanobu Ogawa, Satoshi Oeda, Katsutoshi Sugimoto, Toshifumi Tada, Reiichiro Kondo, Tomoyuki Akita, Shigehiro Kokubu, Yoichi Hiasa, Atsushi Nakajima, Hidenori Toyoda, Hirokazu Takahashi, Yuichiro Eguchi, Hirohisa Yano, Junko Tanaka, Fuminori Moriyasu, Masayoshi Kage, Takashi Kumada   +24 more
wiley   +1 more source

Overlap syndrome: Report of a case and review of the literature.

Annals of Hepatology
Introduction and Objectives: Autoimmune liver disorders, like autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis, are characterized by an atypical immune response that targets bile duct damage in primary biliary ...
Karent I. Méndez-Verdejo, Lourdes Del Follo-Martínez, Jessica A. Rojas-López, Karla D. Sales-Morales   +3 more
doaj   +1 more source

Reduced Coffee Consumption Among Individuals With Primary Sclerosing Cholangitis but Not Primary Biliary Cirrhosis [PDF]

, 2014
Craig Lammert, Brian D. Juran, Erik M. Schlicht, Xiao Xie, Elizabeth J. Atkinson, Mariza de Andrade, Konstantinos N. Lazaridis   +6 more
openalex   +1 more source

Machine Learning Approach Enables Highly Accurate Identification of At‐Risk Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
ABSTRACT Aim At‐risk metabolic dysfunction‐associated steatohepatitis (MASH), characterized by significant activity and fibrosis, increases the risk of liver complications. Liver stiffness measurement (LSM), commonly used to detect significant fibrosis, has limitations in terms of accessibility and performance in certain populations.
Masaya Sato, Takuma Nakatsuka, Tatsuya Minami, Yotaro Kudo, Rie Irie, Hanako Tsujikawa, Takumi Kawaguchi, Hirokazu Takahashi, Yuichiro Eguchi, Eisuke Murakami, Kazuaki Chayama, Takeshi Okanoue, Michiie Sakamoto, Mitsuhiro Fujishiro, Kazuhiko Koike, Ryosuke Tateishi   +15 more
wiley   +1 more source