Results 241 to 250 of about 4,431,933 (293)

Temporal trends in the epidemiology of primary biliary cholangitis in the public healthcare system of Brazil: a large population-based study. [PDF]

Lancet Reg Health Am
Cançado GGL, Couto CA, Faria LC, Moraes BF, Leite GAPD, Bittencourt PL, Vilella-Nogueira CA, Rotman V, Terrabuio DRB, Cançado ELR, Ferraz ML.   +10 more
europepmc   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li, Yong Zhang, Kaishuang Cai, Shaojun Deng, Chaofeng Tan, Yunjie Li, Wenjin Liang   +6 more
wiley   +1 more source

Machine-perfused Donation After Circulatory Death Grafts Improve Access to Liver Transplant for Primary Biliary Cholangitis Patients. [PDF]

Transplant Direct
Kleinertz A, Asassfeh A, Rawashdeh B, Harris M, Battula N, Prasad KR, Raigani S.   +6 more
europepmc   +1 more source

Abnormalities of liver sinusoidal endothelial cells in primary biliary cholangitis. [PDF]

World J Exp Med
Thalassinos E, Notas G, Xidakis C, Drygiannakis I, Sfakianaki O, Tsomidis I, Kouroumalis E.   +6 more
europepmc   +1 more source

The Fibrosis‐4 Index Predicts Ceftriaxone‐Associated Gallstone Formation: Risk Stratification Using the Fibrosis‐4 Index in a Clinical Cohort

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Ceftriaxone is widely used because of its broad antimicrobial spectrum and convenient dosing; however, high biliary excretion can lead to calcium–ceftriaxone precipitation and gallstone‐like formations. Although exposure‐related risk factors have been described, the effect of hepatic fibrosis on ceftriaxone‐associated gallstone ...
Hideo Kato, Mao Hagihara, Hiroshige Mikamo, Takuya Iwamoto   +3 more
wiley   +1 more source

Bile Acid Profiles Define Disease-Specific Cholestatic States in Primary Sclerosing and Primary Biliary Cholangitis. [PDF]

Gastro Hep Adv
Juran BD, McCauley BM, Hu C, Ali AH, Schlicht EM, Bianchi JK, Schell MJ, Atkinson EJ, Hov JR, Vesterhus M, Rosenberg W, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN.   +14 more
europepmc   +1 more source

Five‐Year CT‐Based Skeletal Muscle Decline Curves in Cirrhosis According to Liver Functional Reserve and Routinely Available Clinical Factors

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Sarcopenia is common in cirrhosis and is associated with poor outcomes. We aimed to identify factors associated with longitudinal skeletal muscle loss and to explore estimation of future L3 skeletal muscle index (L3‐SMI) using routinely available clinical variables. Methods This retrospective longitudinal study included 175 patients
Suguru Miida, Hiroteru Kamimura, Hitoshi Yoshiji, Masahito Shimizu, Takumi Kawaguchi, Tetsuya Tsuji, Saori Endo, Hiroki Natsui, Hiroki Maruyama, Hiroyuki Abe, Tadashi Namisaki, Takao Miwa, Dan Nakano, Michiyuki Kawakami, Shuji Terai   +14 more
wiley   +1 more source

Gut microbiota alterations in primary biliary cholangitis: a systematic review and meta-analysis. [PDF]

Front Microbiol
Qianlang R, Yanxin Z, Dejia X, Guoqing W, Lihong L, Hang C, Xianmei W, Junyan L, Lanqing M.   +8 more
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Glucosyl Hesperidin Benefits in Primary Biliary Cholangitis: A Multicenter, Open-Label, Randomized Controlled Study. [PDF]

Clin Transl Gastroenterol
Moriya K, Asada K, Ozu N, Suzuki S, Fujinaga Y, Enomoto M, Tsuji Y, Komeda Y, Hanatani J, Kaya D, Matsuo Y, Nagamatsu S, Matsuo H, Uejima M, Yamazaki M, Yoshiji H.   +15 more
europepmc   +1 more source