Results 271 to 280 of about 4,431,933 (293)

Autoimmune Markers in Primary Biliary Cholangitis.

Clinical Liver Disease, 2023
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. The most common antibody associated with PBC is the anti-mitochondrial antibody (AMA), present in 90% to 95% of patients.
Shivani K. Shah, C. Bowlus
semanticscholar   +1 more source

Primary biliary cholangitis

Medicine, 2023
PBC (formerly known as primary biliary cirrhosis and now named primary biliary cholangitis) is a disease with a wide range of severity and variable rate of progression.
G. Mells
semanticscholar   +1 more source

Primary Biliary Cholangitis: Pathophysiology.

Clinical Liver Disease, 2023
Primary biliary cholangitis (PBC) is the most common of the autoimmune liver diseases, in which there is chronic small bile duct inflammation. The pathophysiology of PBC is multifactorial, involving immune dysregulation and damage to biliary epithelial ...
I. Houri, G. Hirschfield
semanticscholar   +1 more source

Primary Biliary Cholangitis: personalizing second-line therapies.

Hepatology
Primary biliary cholangitis (PBC) is an enigmatic, autoimmune disease targeting the small intralobular bile ducts resulting in cholestasis and potentially progression to biliary cirrhosis.
C. Levy, C. Bowlus
semanticscholar   +1 more source

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Therapy Landscape.

American Journal of Gastroenterology
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are rare, chronic cholestatic diseases that can progress to liver failure. The goals of treatment are to halt the progression of liver disease to cirrhosis and/or liver failure ...
Sheena Bhushan, Aalam Sohal, Kris V. Kowdley, Facg Faasld Agaf   +3 more
semanticscholar   +1 more source

Mechanisms and molecules: What are the treatment targets for primary biliary cholangitis?

Hepatology, 2022
Treatment of primary biliary cholangitis (PBC) with ursodeoxycholic acid (UDCA) is not always sufficient to prevent progression to hepatic decompensation and/or need for liver transplant.
M. Mayo
semanticscholar   +1 more source

Contemporary Epidemiology of Primary Biliary Cholangitis.

Clinical Liver Disease, 2022
Primary biliary cholangitis (PBC) is a cholestatic liver disease with potential evolution to liver cirrhosis when left untreated. Despite being rare, PBC has a substantial impact on the quality of life and survival of affected patients.
F. Colapietro, A. Bertazzoni, A. Lleo
semanticscholar   +1 more source

Primary Biliary Cholangitis

Current treatment options in gastroenterology, 2022
Andrew R. Scheinberg, Cynthia Levy
semanticscholar   +1 more source

New Therapies on the Horizon for Primary Biliary Cholangitis

Drugs, 2023
Atsushi Tanaka
semanticscholar   +1 more source

Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis

Clinical Gastroenterology and Hepatology, 2020
George N Dalekos, Bettina Hansen, Andrew L. Mason   +2 more
exaly