Results 251 to 260 of about 4,431,933 (293)

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan, Ke Tang, Linglong Wang, Qin Tian, Mingwei Zheng, Cheng Qian, Limei Liu   +6 more
wiley   +1 more source

Mechanisms linking primary biliary cholangitis and osteoporosis: A combined clinical and molecular analysis. [PDF]

Medicine (Baltimore)
Li H, Guo X, Fan Q.
europepmc   +1 more source

Optimal Control‐Based RF Pulses Versus Classical Motion‐Encoding Strategies for In Vivo Hepatic MR Elastography Across Multiple Excitation Frequencies in Mice: Reproducibility Assessment

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Optimal control (OC)–based motion encoding doubles SNR in vivo in murine hepatic MRE by eliminating motion‐encoding gradients and enabling shorter echo times. Quantitative liver stiffness measurements remain consistent with conventional MEG‐MRE across multiple excitation frequencies, supporting longitudinal studies and clinical translation ...
Tiffany Bakir‐Ageron, Pilar Sango‐Solanas, Eric Van Reeth, Denis Grenier, Kevin Tse Ve Koon, Olivier Beuf   +5 more
wiley   +1 more source

Development and evaluation of explainable machine learning models for predicting prognosis in patients with primary biliary cholangitis. [PDF]

Front Mol Biosci
Dou Y, Liu J.
europepmc   +1 more source

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, Volume 41, Issue 5, Page 1296-1306, October 2026.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

Primary Biliary Cholangitis Increases Mortality Irrespective of Presence or Absence of Cirrhosis. [PDF]

Liver Int
Bossen L, Grønbæk H, Ott P, Jepsen P.
europepmc   +1 more source

Gastrointestinal adverse effects of GLP‐1 receptor agonists and dual GIP/GLP‐1 receptor agonists: A narrative expert review of approved therapies, oral formulations, and pipeline agents

Nutrition in Clinical Practice, Volume 41, Issue 5, Page 1318-1333, October 2026.
Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonists have transformed the management of type 2 diabetes and obesity. Gastrointestinal (GI) adverse events are the most common limitation of these therapies and a leading cause of discontinuation ...
Vikash Singhani, Muhammad Ehsan, Sara Valencia, Ahmed Nadeem, Eisha Moazzam, Winfield Scott Butsch, Samita Garg   +6 more
wiley   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Prognostic nutritional index as a predictor of ursodeoxycholic acid response in primary biliary cholangitis: a retrospective study. [PDF]

BMC Gastroenterol
Zheng M, Lei H, He H, Huang Y, Zhu H, Lin H, Fu W, Tai W, Wang Y, Yang J.   +9 more
europepmc   +1 more source

Autoantibodies in the diagnostics, prognostics and follow-up of primary biliary cholangitis. [PDF]

J Transl Autoimmun
Antal-Szalmás P, Bencze D, Demeter S, Pénzes-Daku K, Szabó L, Tóth B, Földesi R, Papp M, Nagy G.   +8 more
europepmc   +1 more source