Results 21 to 30 of about 25,833,379 (292)

Cerebellar large B-cell lymphoma: a case report

Journal of Medical Case Reports, 2018
Background Primary central nervous system lymphoma is a rare, malignant non-Hodgkin lymphoma that can arise in the brain, spinal cord, eye, leptomeninges, or cranial nerves.
Malik Ghannam, Shaden Mansour, Fareed Jumah, Brent Berry, Albertine Beard   +4 more
doaj   +1 more source

The genomic and transcriptional landscape of primary central nervous system lymphoma

Nature Communications, 2022
Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell lymphomas (DLBCLs) confined to the central nervous system (CNS). Molecular drivers of PCNSL have not been fully elucidated.
Josefine Radke, N. Ishaque, Randi Koll, Zu-Guang Gu, Elisa Schumann, Lina Sieverling, Sebastian Uhrig, Daniel Hübschmann, Umut H. Toprak, Cristina López, Xavier Pastor Hostench, Simone Borgoni, Dilafruz Juraeva, Fabienne Pritsch, Nagarajan Paramasivam, G. Balasubramanian, Matthias Schlesner, Shashwat Sahay, Marc Weniger, Debora Pehl, Helena Radbruch, Anja Osterloh, Agnieszka Korfel, Martin Misch, Julia Onken, Katharina Faust, Peter Vajkoczy, Dag Moskopp, Ya-Wen Wang, Andreas Jödicke, Lorenz Trümper, Ioannis Anagnostopoulos, Dido Lenze, Ralf Küppers, Michael Hummel, Clemens A. Schmitt, Otmar D. Wiestler, Stephan Wolf, Andreas Unterberg, Roland Eils, Christel Herold-Mende, Benedikt Brors, Reiner Siebert, Stefan Wiemann, Frank L. Heppner   +44 more
semanticscholar   +1 more source

European Association of Neuro-Oncology (EANO) Guidelines for Treatment of Primary Central Nervous System lymphoma (PCNSL).

Neuro-Oncology, 2022
The management of primary central nervous system (PCNSL) is one of the most controversial topics in neuro-oncology because of the complexity of the disease and the limited number of controlled studies available.
K. Hoang-Xuan, M. Deckert, A. Ferreri, J. Furtner, Jaime Gállego Pérez-Larraya, R. Henriksson, A. Hottinger, B. Kasenda, F. Lefranc, A. Lossos, C. Mcbain, M. Preusser, P. Roth, R. Rudà, U. Schlegel, R. Soffietti, C. Soussain, M. Taphoorn, V. Touitou, Michael Weller, J. Bromberg   +20 more
semanticscholar   +1 more source

HIV Related Primary Central Nervous System Lymphoma: Case Study

Turkish Journal of Internal Medicine, 2021
Cranial imaging is vital in patients with complaints of sudden speech disorder, deterioration in performance status, urinary and fecal incontinence, and numbness in hands and feet.
Cumali Yalçın, Gül Ada, Rıdvan Ali, Fahir Özkalemkaş, Vildan Ozkocaman, Tuba Ersal, İbrahim Ethem Pınar, Bedrettin Orhan   +7 more
doaj   +1 more source

Patient‐derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma

, 2023
AimsHow and why lymphoma cells home to the central nervous system and vitreoretinal compartment in primary diffuse large B-cell lymphoma of the central nervous system remain unknown.
Hans Eckart Schaefer, Lisa Kristina Isbell, Boerries, Melanie, Melanie Boerries, Schüler, Julia, Vinodh Kakkassery, Duyster, Justus, Gerald Illerhaus, Illerhaus, Gerald, Tschuch, Cordula, Reinacher, Peter C., Schorb, Elisabeth, Justus Duyster, Frey, Anna-Verena, Geoffroy Andrieux, Dorothee Lenhard, Lenhard, Dorothée, Schueler, Julia, Scherer, Florian, Kakkassery, Vinodh, Shoumariyeh, Khalid, Pantic, Milena, Julia Schueler, Reinacher, Peter Christoph, Janaki Manoja Vinnakota, Khalid Shoumariyeh, Isbell, Lisa Kristina, Milena Pantic, Anna Verena Frey, Vinnakota, Janaki Manoja, Peter Christoph Reinacher, Doostkam, Soroush, Soroush Doostkam, Andrieux, Geoffroy, Frey, Anna Verena, Waldeck, Silvia, Scherer, Florian Paul, Nikolas von Bubnoff, Schaefer, Hans Eckart, Cordula Tschuch, Schaefer, Hans-Eckart, Elisabeth Schorb, Florian Scherer, Bartsch, Ingrid, Bubnoff, Nikolas von, Silvia Waldeck, Ingrid Bartsch   +46 more
core   +1 more source

Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG)

Neuro-Oncology, 2021
Advanced molecular and pathophysiologic characterization of primary central nervous system lymphoma (PCNSL) has revealed insights into promising targeted therapeutic approaches.
Ramon F. Barajas, L. Politi, N. Anzalone, H. Schöder, C. Fox, J. Boxerman, T. Kaufmann, C. Quarles, B. Ellingson, Dorothee P Auer, O. Andronesi, A. Ferreri, M. Mrugala, C. Grommes, E. Neuwelt, P. Ambady, J. Rubenstein, G. Illerhaus, M. Nagane, T. Batchelor, Leland S. Hu   +20 more
semanticscholar   +1 more source

Longitudinally extensive transverse myelitis preceding primary central nervous system lymphoma: Spinal sentinel neuroinflammation

, 2022
Case Description: 65-year-old female diagnosed with longitudinally extensive transverse myelitis. She had excellent response to immunotherapy despite her atypical features, and her spinal lesion was fully recovered in the second month of the treatment ...
Salihoğlu, Ayşe, Ser, Merve Hazal, Uygunoğlu, Uğur, Güleç, Bade   +3 more
core   +1 more source

Spatial single cell analysis of tumor microenvironment remodeling pattern in primary central nervous system lymphoma

Leukemia, 2023
To determine the overall tumor microenvironment (TME), characteristics, and transition mechanisms in primary central nervous system lymphoma (PCNSL), we performed spatial transcriptomics and matched the corresponding single-cell sequencing data of PCNSL ...
Yuan-sheng Xia, Tao Sun, Guosheng Li, Mingying Li, Dong-Mei Wang, Xiu-Hua Su, Jingjing Ye, C. Ji   +7 more
semanticscholar   +1 more source

Primary central nervous system lymphoma as a neurosurgical problem [PDF]

, 1970
Primary central nervous system lymphoma (PCNSL) comprises around 3–5% of primary central nervous system (CNS) tumours and around 1% of all non-Hodgkin lymphoma (NHL). Diffuse large B-cell lymphoma (DLBCL) is the most common histological type.
Stoma, Filip; Department of Neurosurgery and Paediatric Neurosurgery, Medical University in Lublin, Poland, Sokołowska, Bożena; Department of Haematooncology and Bone Marrow Transplantation, Medical University in Lublin, Poland, Trojanowski, Tomasz; Department of Neurosurgery and Paediatric Neurosurgery, Medical University in Lublin, Poland, Szczepanek, Dariusz; Department of Neurosurgery and Paediatric Neurosurgery, Medical University in Lublin, Poland, Wąsik-Szczepanek, Ewa; Department of Haematooncology and Bone Marrow Transplantation, Medical University in Lublin, Poland   +4 more
core   +1 more source

Primary central nervous system lymphoma in the United States, 1975–2017

Therapeutic Advances in Hematology, 2022
Background: Primary central nervous system lymphoma (PCNSL) has received more attention because of an inferior prognosis. Less is known about the incidence rate, histological type, and survival rate of PCNSL, especially in the 2010s.
Chenglan Lv, Jing Wang, Min Zhou, Jing-Yan Xu, Bing Chen, Yuan Wan   +5 more
semanticscholar   +1 more source