Results 31 to 40 of about 25,833,379 (292)

Radiation therapy for primary central nervous system lymphoma

open access: yesOncology Reviews, 2013
Up until the late 1970s, radiation therapy played an important role in the treatment of primary central nervous system lymphoma (PCNSL) but more recently its role has changed due to the increased use of systemic chemotherapy. In this article, the current
Yuta Shibamoto
doaj   +1 more source

Molecular and clinical diversity in primary central nervous system lymphoma.

open access: yesAnnals of Oncology, 2022
BACKGROUND Primary central nervous system lymphoma (PCNSL) is a rare and distinct entity within diffuse large B cell lymphoma presenting with variable response rates probably to underlying molecular heterogeneity.
I. Hernández-Verdin   +37 more
semanticscholar   +1 more source

Primary central nervous system lymphoma in neurosurgery [PDF]

open access: yes, 2021
Primary central nervous system lymphoma (PCNSL) most commonly (>95%) constitutes a specific kind of diffuse large B-cell lymphoma, which shows expression of CD20, CD19 and CD79a antigens on its surface and belongs to non-germinal center B-cell-like ...
Stoma, Filip; Department of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, Lublin, Poland   +2 more
core   +1 more source

Evidence-based expert consensus on the management of primary central nervous system lymphoma in China

open access: yesJournal of Hematology & Oncology, 2022
Primary central nervous system lymphoma (PCNSL) is a type of central nervous system restricted non-Hodgkin lymphoma, whose histopathological diagnosis is majorly large B cell lymphoma.
Tong Chen   +24 more
semanticscholar   +1 more source

Orelabrutinib Combined With Lenalidomide and Immunochemotherapy for Relapsed/Refractory Primary Central Nervous System Lymphoma: A Retrospective Analysis of Case Series

open access: yesFrontiers in Oncology, 2022
Background Relapsed/refractory (r/r) primary central nervous system lymphoma (PCNSL) is an intractable situation without sound treatment. Bruton’s tyrosine kinase (BTK) represents an attractive drug target in PCNSL.
Chuanwei Yang   +11 more
semanticscholar   +1 more source

MYD88 L265P mutation and interleukin‐10 detection in cerebrospinal fluid are highly specific discriminating markers in patients with primary central nervous system lymphoma: results from a prospective study

open access: yesBritish Journal of Haematology, 2021
Reliable biomarkers are needed to avoid diagnostic delay and its devastating effects in patients with primary central nervous system (CNS) lymphoma (PCNSL).
A. Ferreri   +33 more
semanticscholar   +1 more source

Primary cardiac lymphoma with central nervous system relapse

open access: yesClinical Case Reports, 2017
Key Clinical Message Primary cardiac lymphoma (PCL), a rare disease, often presents with symptoms resembling other cardiac diseases. The correct diagnosis is crucial, as cardiac lymphoma can be cured with immuno‐chemotherapy.
Cleo R. vanRooijen   +4 more
doaj   +1 more source

Primary Malignant Lymphoma Presenting as an Isolated Epidural Mass

open access: yesDiagnostics, 2022
Primary central nervous system lymphoma is a rare form of extranodal non-Hodgkin’s lymphoma that occurs in the brain, spinal cord, leptomeninges, or eyes and typically remains confined to the central nervous system.
Haksung Kim, Daekyun Kim, Seokwon Kim
doaj   +1 more source

Phase I/II study of tirabrutinib, a second-generation Bruton’s tyrosine kinase inhibitor, in relapsed/refractory primary central nervous system lymphoma

open access: yesNeuro-Oncology, 2020
Background The safety, tolerability, efficacy, and pharmacokinetics of tirabrutinib, a second-generation, highly selective oral Bruton’s tyrosine kinase inhibitor, were evaluated for relapsed/refractory primary central nervous system lymphoma (PCNSL ...
Y. Narita   +12 more
semanticscholar   +1 more source

Outcomes Associated With Thiotepa-Based Conditioning in Patients With Primary Central Nervous System Lymphoma After Autologous Hematopoietic Cell Transplant.

open access: yesJAMA Oncology, 2021
Importance Primary central nervous system lymphoma (PCNSL) requires induction and consolidation to achieve potential cure. High-dose therapy and autologous hematopoietic cell transplant (AHCT) is an accepted and effective consolidation strategy for PCNSL,
M. Scordo   +38 more
semanticscholar   +1 more source

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