Results 61 to 70 of about 25,833,379 (292)

A case report of primary central nervous system lymphoma

open access: yesJournal of International Medical Research, 2020
Most patients with primary central system lymphoma (PCNSL) have immune dysfunction. PCNSL without immune dysfunction is rare and extremely challenging to diagnose.
Xu Zeng   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Updates of primary central nervous system lymphoma

open access: yesTherapeutic Advances in Hematology
Lymphoma occurring in the central nervous system is considered primary central nervous system lymphoma (PCNSL), usually without systematic lesions. Over the last few decades, a deep understanding of PCNSL has been lacking due to the low incidence rate ...
Jiaying Wu   +4 more
doaj   +1 more source

Diagnosis, prognosis and treatment of primary central nervous system lymphoma in the elderly population (Review)

open access: yesInternational Journal of Oncology, 2021
Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non-Hodgkin lymphoma that is unique and different from systemic diffuse large B-cell lymphomas.
Yan-xia Liu, Qing-min Yao, Feng Zhang
semanticscholar   +1 more source

Chemokine microenvironment in primary central nervous system lymphoma [PDF]

open access: yes, 2010
Primary central nervous system lymphomas (PCNSL) are aggressive extranodal malignancies confined to the central nervous system (CNS), mostly of diffuse large B cell histotype.
Venetz, Daniel
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

An unusual presentation of lymphoma

open access: yesCurrent Problems in Cancer: Case Reports, 2021
This case illustrates an unusual presentation of diffuse large B cell lymphoma (DLBCL) with florid central nervous system disease and an isolated right coronary artery lesion.
Christopher Shwei Wen Tham   +6 more
doaj   +1 more source

PRIMARY CAUDA EQUINA LYMPHOMA : CASE REPORT AND LITERATURE REVIEW [PDF]

open access: yes, 2014
2014-08The central nervous system, in particular the spinal cord, is a rare site for primary lymphoma occurrence, with very few published cases. We report an extremely rare primary lymphoma in the cauda equina in a single case with literature review.
UKAI, JUNICHI   +11 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

open access: yesAdvanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo   +10 more
wiley   +1 more source

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