Results 91 to 100 of about 4,814,966 (373)
Kinematics of the most efficient cilium [PDF]
Phys. Rev. Lett. 109, 038101 (2012), 2012 In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this diversity, we determine numerically the kinematics and energetics of the most efficient cilium.
arxiv +1 more source
The FEBS Journal, 2020 The primary cilium is a microtubule‐based structure that protrudes from the cell surface in diverse eukaryotic organisms. It functions as a key signaling center that decodes a variety of mechanical and chemical stimuli and plays fundamental roles in ...
Deniz Conkar, E. N. Firat-Karalar
semanticscholar +1 more source
The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length [PDF]
, 2018 Axonemal dyneins, including inner dynein arm I1, assemble in the cytoplasm prior to transport into cilia by intraflagellar transport (IFT). How I1 dynein interacts with IFT is not understood.
Alford, Lea M +14 more
core +2 more sources
Primary cilia elongation in response to interleukin-1 mediates the inflammatory response [PDF]
, 2012 Primary cilia are singular, cytoskeletal organelles present in the majority of mammalian cell types where they function as coordinating centres for mechanotransduction, Wnt and hedgehog signalling. The length of the primary cilium is proposed to modulate
A. K. T. Wann +51 more
core +2 more sources
New Roles of the Primary Cilium in Autophagy [PDF]
BioMed Research International, 2017 The primary cilium is a nonmotile organelle that emanates from the surface of multiple cell types and receives signals from the environment to regulate intracellular signaling pathways. The presence of cilia, as well as their length, is important for proper cell function; shortened, elongated, or absent cilia are associated with pathological conditions.
Yenniffer Ávalos +4 more
openaire +3 more sources
Hydrodynamic flow patterns and synchronization of beating cilia [PDF]
Phys. Rev. Lett. 96, 058102 (2006), 2005 We calculate the hydrodynamic flow field generated far from a cilium which is attached to a surface and beats periodically. In the case of two beating cilia, hydrodynamic interactions can lead to synchronization of the cilia, which are nonlinear oscillators.
arxiv +1 more source
Thermodynamic cost of synchronizing a population of beating cilia [PDF]
J. Stat. Mech. (2020) 074001, 2020 Synchronization among arrays of beating cilia is one of the emergent phenomena in biological processes at meso-scopic scales. Strong inter-ciliary couplings modify the natural beating frequencies, $\omega$, of individual cilia to produce a collective motion that moves around a group frequency $\omega_m$.
arxiv +1 more source
Fluid mechanics of nodal flow due to embryonic primary cilia [PDF]
, 2008 Breaking of left–right symmetry is crucial in vertebrate development. The role of cilia-driven flow has been the subject of many recent publications, but the underlying mechanisms remain controversial.
Blake, J R, Gaffney, E. A., Smith, D J
core +2 more sources
Hook2 is involved in the morphogenesis of the primary cilium
Molecular Biology of the Cell, 2011 Primary cilia originate from the centrosome and play essential roles in several cellular, developmental, and pathological processes, but the underlying mechanisms of ciliogenesis are not fully understood. Given the involvement of the adaptor protein Hook2 in centrosomal homeostasis and protein transport to pericentrosomal aggresomes, we explored its ...
Jean-Paul Borg +11 more
openaire +6 more sources
Stem Cell Research, 2020 The primary cilium acts as a sensory organelle with diverse receptors and ion channels to detect extracellular cues and regulate cellular functions, including cell migration.
Mi Nam Lee +7 more
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