Results 71 to 80 of about 4,304,152 (140)
Mechanics & Dynamics of the Primary Cilium [PDF]
, 2013 Recent studies have shown that the primary cilium, long thought to be a vestigial organelle with no function, is involved in a multitude of sensory functions.
Battle, Christopher
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Cilium-localized CK1γ promotes Smo phosphorylation and Shh pathway activity.
, 2016 (A) NIH3T3 transfected with EYFP-CK1γ or EYFP-CK1γ-ΔC were immunostained with antibodies against acetylated tubulin (Ac-Tub), GFP, and Hoechst. EYFP-CK1γ but not EYFP-CK1γ-ΔC was localized on the primary cilium. (B–D) Gli-luciferase assay in NIH3T3 cells
Shuang Li (146392) +6 more
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Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding.
PLoS Biology, 2019 The primary cilium is a central signaling hub in cell proliferation and differentiation and is built and disassembled every cell cycle in many animal cells.
Mary Mirvis +3 more
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PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts [PDF]
, 2005 SummaryRecent findings show that cilia are sensory organelles that display specific receptors and ion channels, which transmit signals from the extracellular environment via the cilium to the cell to control tissue homeostasis and function [1–6 ...
Else K. Hoffmann +18 more
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Glucose deprivation induces primary cilium formation through mTORC1 inactivation
, 2017 Primary cilia are antenna-like sensory organelles extending from the surface of many cell types and play critical roles in tissue development and homeostasis. Here, we examined the effect of nutrient status on primary cilium formation.
Kengo Takahashi +4 more
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Primary cilia: the chemical antenna regulating human adipose-derived stem cell osteogenesis.
PLoS ONE, 2013 Adipose-derived stem cells (ASC) are multipotent stem cells that show great potential as a cell source for osteogenic tissue replacements and it is critical to understand the underlying mechanisms of lineage specification.
Josephine C Bodle +6 more
doaj +1 more source
Primary cilium in CO25 cell line
, 2003 15th Annual Meeting of the Japanese-Association-for-Animal-Cell-Technology -- NOV 11-15, 2002 -- Fuchu, JAPANWOS: 000222558600085A few variety of cell type contain a primary cilium.
Zeytinoğlu, Melih, Ocak, HY
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The Primary Cilium as a Complex Signaling Center
, 2009 Respect for the primary cilium has undergone a remarkable renaissance over the past decade, and it is now thought to be an essential regulator of numerous signaling pathways.
Berbari, Nicolas F. +8 more
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Dynamics of the Primary Cilium in Shear Flow
, 2020 In this work, the equilibrium shape and dynamics of a primary cilium under flow are investigated by using both theoretical modeling and experiment. The cilium is modeled as an elastic beam that may undergo large deflection due to the hydrodynamic load ...
‡, M Downs, C R Jacobs, Y.-N Young
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Factors That Influence Primary Cilium Length
Almost all mammalian cells carry one primary cilium that functions as a biosensor for chemical and mechanical stimuli. Genetic damages that compromise cilia formation or function cause a spectrum of disorders referred to as ciliapathies.
Miyazaki, Ikuko +3 more
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