Results 61 to 70 of about 20,808 (274)
DataSheet1_Dendritic cell proliferation by primary cilium in atopic dermatitis.pdf
, 2023 Introduction: Atopic dermatitis (AD) is a common allergic eczema that affects up to 10% of adults in developed countries. Immune cells in the epidermis, namely, Langerhans cells (LCs), contribute to the pathogenesis of AD, although their exact role(s) in
Fumitaka Fujita (4164472) +9 more
core +1 more source
Location of Smoothened Protein in Primary Cilium
, 2023 The primary cilium is an important organelle that facilitates numerous signaling pathways and delivers extracellular signals into the cell. Among those pathways is the Hedgehog (HH) signaling pathway, which has an important role in bone formation ...
Íris Ósk Halldórsdóttir 1999-
core +1 more source
Pathophysiology of Primary Cilia: Signaling and Proteostasis Regulation
Frontiers in Cell and Developmental Biology, 2022 Primary cilia are microtubule-based, non-motile sensory organelles present in most types of growth-arrested eukaryotic cells. They are transduction hubs that receive and transmit external signals to the cells in order to control growth, differentiation ...
Emanuela Senatore +5 more
doaj +1 more source
DataSheet1_Dendritic cell proliferation by primary cilium in atopic dermatitis.docx
, 2023 Introduction: Atopic dermatitis (AD) is a common allergic eczema that affects up to 10% of adults in developed countries. Immune cells in the epidermis, namely, Langerhans cells (LCs), contribute to the pathogenesis of AD, although their exact role(s) in
Fumitaka Fujita (4164472) +19 more
core +1 more source
Long-pentraxin 3 affects primary cilium in zebrafish embryo and cancer cells via the fgf system [PDF]
, 2020 Primary cilium drives the left-right asymmetry process during embryonic development. Moreover, its dysregulation contributes to cancer progression by affecting various signaling pathways.
Jessica Guerra +9 more
core +3 more sources
NPHP proteins are binding partners of nucleoporins at the base of the primary cilium.
PLoS ONE, 2019 Cilia are microtubule-based organelles that protrude from the surface of eukaryotic cells to generate motility and to sense and respond to environmental cues.
T Lynne Blasius +2 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Cell Reports, 2018 Summary: Primary cilia are sensory organelles that protrude from the cell membrane. Defects in the primary cilium cause ciliopathy disorders, with retinal degeneration as a prominent phenotype.
Helen Louise May-Simera +25 more
doaj +1 more source
Review of Thermally Activated Twisted Coiled Polymer Actuators: A Materials Science Perspective
Advanced Functional Materials, EarlyView.Thermally activated twisted and coiled polymer actuators (TCPAs) combine lightweight design, large deformation, and scalable fabrication for soft robotic and wearable applications. This review connects polymer structure, processing history, helix geometry, and thermomechanical characterization to actuator performance, highlighting current challenges in
Nadja Schenk +3 more
wiley +1 more source