Results 41 to 50 of about 5,628,138 (356)

GPR161 mechanosensitivity at the primary cilium drives neuronal saltatory migration. [PDF]

Sci Adv
Paillard T, Allam A, Doulazmi M, Hautefeuille M, Fouquet C, Sarde L, Stoufflet J, Messaoudi S, Spassky N, Nédélec S, Dusart I, Trembleau A, Isabelle Caillé.   +12 more
europepmc   +2 more sources

Control of the Hedgehog pathway by compartmentalized PKA in the primary cilium

Science China Life Sciences, 2021
Eva Cai, Jingyi Zhang, Xuecai Ge
openalex   +3 more sources

Hedgehog pathway, cell cycle, and primary cilium. [PDF]

Cell Death Discov
Zhuang T.
europepmc   +3 more sources

Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance Imbalance between neural cell proliferation and neuronal differentiation during development can result in pediatric cancer or neurodevelopmental disorders.
S. Shim, Raman Goyal, A. Panoutsopoulos, O. Balashova, David K. Lee, L. Borodinsky   +5 more
semanticscholar   +1 more source

The importance of a single primary cilium [PDF]

Organogenesis, 2013
The centrosome is the main microtubule-organizing center in animal cells, and helps to influence the morphology of the microtubule cytoskeleton in interphase and mitosis. The centrosome also templates the assembly of the primary cilium, and together they serve as a nexus of cell signaling that provide cells with diverse organization, motility, and ...
Moe R. Mahjoub
openalex   +4 more sources

Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron Model

Cells, 2023
The primary cilium plays critical roles in the homeostasis and development of neurons. Recent studies demonstrate that cilium length is regulated by the metabolic state of cells, as dictated by processes such as glucose flux and O-GlcNAcylation (OGN ...
Jie L. Tian, Chia-Wei Huang, Farzad Eslami, Michael Philip Mannino, Rebecca Lee Mai, Gerald W. Hart   +5 more
doaj   +1 more source

Bioinformatics analyses of the proteome of <i>Holothuria tubulosa</i> coelomic fluid and the first evidence of primary cilium in coelomocyte cells. [PDF]

Front Immunol
La Paglia L, Mauro M, Arizza V, Urso A, Simon S, Drahos L, di Stefano V, Luparello C, Vazzana M, Vizzini A.   +9 more
europepmc   +3 more sources

Adenylate Cyclase Type III Is Not a Ubiquitous Marker for All Primary Cilia during Development. [PDF]

PLoS ONE, 2017
Adenylate cyclase type III (AC3) is localized in plasma membrane of neuronal primary cilium and can be used as a marker of this cilium. AC3 has also been detected in some other primary cilia such as those of fibroblasts, synoviocytes or astrocytes ...
Maria Cristina Antal, Karelle Bénardais, Brigitte Samama, Cyril Auger, Valérie Schini-Kerth, Said Ghandour, Nelly Boehm   +6 more
doaj   +1 more source

CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins.

Journal of Cell Science, 2023
The primary cilium is a microtubule-based organelle that serves as a hub for many signaling pathways. It functions as part of the centrosome/cilium complex, which also contains the basal body and the centriolar satellites.
Ezgi Odabasi, Deniz Conkar, J. Deretic, Umut Batman, K. M. Frikstad, S. Patzke, E. N. Firat-Karalar   +6 more
semanticscholar   +1 more source

The multifaceted roles of microtubule-associated proteins in the primary cilium and ciliopathies.

Journal of Cell Science, 2023
The primary cilium is a conserved microtubule-based organelle that is critical for transducing developmental, sensory and homeostatic signaling pathways.
J. Deretic, Ezgi Odabasi, E. N. Firat-Karalar   +2 more
semanticscholar   +1 more source