Results 201 to 210 of about 4,814,966 (373)

Some cognitive transformations about the dynamics of desistance

Criminology &Public Policy, Volume 21, Issue 4, Page 787-809, November 2022., 2022
Abstract This article explores the role of cognitive transformations in the process of desistance from crime. Based on our own and others’ subsequent research, clearly, some aspects of our initial theorizing warrant revisiting and adjustment. The discussion describes changes to ideas about the sequencing of various types of cognitive shifts, suggests ...
Peggy C. Giordano
wiley   +1 more source

Designing metachronal waves of cilia [PDF]

arXiv, 2020
On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via systematic coarse-graining.
arxiv  

Cadherin-7 enhances Sonic Hedgehog signalling by preventing Gli3 repressor formation during neural tube patterning [PDF]

, 2017
Sonic Hedgehog (Shh) is a ventrally enriched morphogen controlling dorsoventral patterning of the neural tube. In the dorsal spinal cord, Gli3 protein bound to suppressor-of-fused (Sufu) is converted into Gli3 repressor (Gli3R), which inhibits Shh-target
Kawano, Rie, Lupo, Giuseppe, Ohta, Kunimasa   +2 more
core   +1 more source

The cholangiocyte primary cilium in health and disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018
Cholangiocytes, like most cells, express primary cilia extending from their membranes. These organelles function as antennae which detect stimuli from bile and transmit the information into cells regulating several signaling pathways involved in secretion, proliferation and apoptosis. The ability of primary cilia to detect different signals is provided
Sujeong Jin, Estanislao Peixoto, Kristen M. Thelen, Adrian P. Mansini, Sergio A. Gradilone, Cesar I. Gaspari   +5 more
openaire   +3 more sources

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Technical Report: Performance Comparison of Service Mesh Frameworks: the MTLS Test Case [PDF]

arXiv
Service Mesh has become essential for modern cloud-native applications by abstracting communication between microservices and providing zero-trust security, observability, and advanced traffic control without requiring code changes. This allows developers to leverage new network capabilities and focus on application logic without managing network ...
arxiv  

The Meckel–Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation [PDF]

, 2006
Helen R. Dawe, Ursula M. Smith, Andrew R. Cullinane, Dianne Gerrelli, P. Cox, José L. Badano, Sarah Blair-Reid, Nisha Sriram, Nicholas Katsanis, Tania Attié‐Bitach, Simon C. Afford, Andrew J. Copp, Déirdre Kelly, Keith Gull, Colin A. Johnson   +14 more
openalex   +1 more source

Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development

Developmental Dynamics, EarlyView.
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin, Ange Michelle Nguimtsop, Fatima N. Chaudhry, Sylvia N. Michki, Jocelynda Salvador, M. Luisa Iruela‐Arispe, Jarod A. Zepp, Saikat Mukhopadhyay, Ondine Cleaver   +8 more
wiley   +1 more source

Galectin-3 Associates with the Primary Cilium and Modulates Cyst Growth in Congenital Polycystic Kidney Disease [PDF]

, 2006
Miliyun G. Chiu, Tanya M. Johnson, Adrian S. Woolf, Eugenia M. Dahm-Vicker, David A. Long, Lisa M. Guay‐Woodford, Katherine A. Hillman, Suleman Bawumia, Kerrie Venner, R. Colin Hughes, Françoise Poirier, Paul J.D. Winyard   +11 more
openalex   +1 more source

Interspecific comparisons of anuran embryonic epidermal landscapes and energetic trade‐offs in response to changes in salinity

Developmental Dynamics, EarlyView.
Abstract Background Freshwater salinization is an emerging stressor in amphibian populations, and embryonic stages are most vulnerable. To better understand the variation in embryonic osmoregulation, we challenged embryos of two phylogenetically diverse anuran species, Xenopus laevis and Lithobates (Rana) sylvaticus, along a gradient of non‐lethal ...
Kourtnie Whitfield, Erica J. Crespi
wiley   +1 more source