Interdisciplinary Medicine, EarlyView.In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun +13 more
wiley +1 more source
Primary Cilium-dependent Humoral Bioactive Factors Acts in a Paracrine Manner to Control Fibroblast Cell Migration [PDF]
Faryal Ijaz, Koshi Imami, Koji Ikegami
openalex +1 more source
JCPP Advances, EarlyView.This study found that shame is a significant mediator in positive associations between hairpulling severity and depression and anxiety severity within a community sample of adolescents with clinical levels of hair‐pulling severity. It also found high levels of trance‐pulling and post‐pulling rituals.
Talia F. Mayerson +2 more
wiley +1 more source
Disrupting the Chain of Displaced Aggression: A Review and Agenda for Future Research
Journal of Organizational Behavior, EarlyView.ABSTRACT Displaced aggression refers to instances in which a person redirects their harm‐doing behavior from a primary to a secondary, substitute target. Since the publication of the first empirical article in 1948, there has been a noticeable surge in research referencing this theory in both management and psychology journals.
Constantin Lagios +4 more
wiley +1 more source
Bi-allelic Mutations in FAM149B1 Cause Abnormal Primary Cilium and a Range of Ciliopathy Phenotypes in Humans [PDF]
, 2019 Ranad Shaheen +18 more
openalex +1 more source
CCDC66 regulates primary cilium length and signaling competence via multi-site interactions with transition zone and axonemal proteins [PDF]
, 2022 Deniz Conkar +6 more
openalex +1 more source
Case series: Joubert syndrome and eosinophilic esophagitis
JPGN Reports, EarlyView.Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening +5 more
wiley +1 more source
Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments. [PDF]
, 2011 Sensory cilia are assembled and maintained by kinesin-2-dependent intraflagellar transport (IFT). We investigated whether two Caenorhabditis elegans α- and β-tubulin isotypes, identified through mutants that lack their cilium distal segments, are ...
Acar, Seyda +8 more
core
Ocular facial myositis and sialadenitis presenting with new onset ulcerative colitis
JPGN Reports, EarlyView.Abstract Extra‐intestinal manifestations of inflammatory bowel disease (IBD) can involve most organ systems, although the immunologic underpinnings are not well understood. Most patients who present with an extra‐intestinal manifestation have a single site of extra‐intestinal involvement; however, a small cohort presents with multiple different sites ...
Nicole Du, Nicole Mendez, Anil Darbari
wiley +1 more source
Loss of a primary cilium in PDAC [PDF]
Cell Cycle, 2017 Tetsuo, Kobayashi, Hiroshi, Itoh
openaire +2 more sources