Results 211 to 220 of about 4,814,966 (373)
Renal Cystic Disease: The Role of the Primary Cilium/Centrosome Complex in Pathogenesis [PDF]
Brian J. Siroky, Lisa M. Guay‐Woodford
openalex +1 more source
Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
wiley +1 more source
New neurons, referred to as neuroblasts, are continuously generated in the ventricular-subventricular zone of the brain throughout an animal's life. These neuroblasts are characterized by their unique potential for proliferation, formation of chain-like ...
Mami Matsumoto+17 more
semanticscholar +1 more source
Active colloidal chains with cilia- and flagella-like motion [PDF]
It has been shown that self-assembled chains of active colloidal particles can present sustained oscillations. These oscillations are possible because of the effective diffusiophoretic forces that mediate the interactions of colloids do not respect the action--reaction principle and hence, a Hopf bifurcation is possible even for overdamped dynamics ...
arxiv
The mammalian Nek1 kinase is involved in primary cilium formation [PDF]
Ohad Shalom+3 more
openalex +1 more source
Abstract Background Mouse nodal immotile cilia mechanically sense the bending direction for left–right (L–R) determination and activate the left‐side‐specific signaling cascade, leading to increased Nodal activity. Asymmetric distribution of Pkd2, a crucial channel for L–R determination, on immotile cilia has been reported recently. However, the causal
Takanobu A. Katoh+5 more
wiley +1 more source
Spatiotemporal distribution of neural crest cells in the common wall lizard Podarcis muralis
Abstract Background Neural crest cells (NCCs) are migratory embryonic stem cells that give rise to a diverse set of cell types. Here we describe the dynamic distribution of NCCs in developing embryos of the common wall lizard Podarcis muralis inferred from 10 markers.
Robin Pranter, Nathalie Feiner
wiley +1 more source
Primary cilia are required for the persistence of memory and stabilization of perineuronal nets
Summary: It is well established that the formation of episodic memories requires multiple hippocampal mechanisms operating on different time scales.
Vladimir Jovasevic+7 more
doaj
Abstract Due to the limited regenerative capacity in adult mammals, the loss of vestibular hair cells (HCs) leads to balance disorders. In this study, we chronologically reprogrammed adult vestibular supporting cells (SCs) via bimodal regulation of Notch signaling, mimicking dynamic changes in Notch signaling during inner ear development. We found that
Shan Zeng+5 more
wiley +1 more source
Primary cilium-mediated mechanotransduction in cartilage chondrocytes. [PDF]
Zhang Y+7 more
europepmc +1 more source