Results 211 to 220 of about 18,376 (272)

[Primary cilium acts as an oxygen sensor in PC12 cells]. [PDF]

, 2017
Yuhai Gao, Xinzhu Qi, Jian Zhou, Xin Wang, Keming Chen, Huiping Ma   +5 more
openalex   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, EarlyView.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Chlamydia trachomatis induces disassembly of the primary cilium to promote the intracellular infection. [PDF]

PLoS Pathog
Ekka R, Gutierrez A, Johnson KA, Tan M, Sütterlin C.   +4 more
europepmc   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade. [PDF]

PLoS Biol
Walker MF, Zhang J, Steiner W, Ku PI, Zhu JF, Michaelson Z, Yen YC, Lee A, Long AB, Casey MJ, Poddar A, Nelson IB, Arveseth CD, Nagel F, Clough R, LaPotin S, Kwan KM, Schulz S, Stewart RA, Tesmer JJG, Caspary T, Subramanian R, Ge X, Myers BR.   +23 more
europepmc   +1 more source

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase [PDF]

, 2019
Michaela Kunova Bosakova, Alexandru Niţă, Tomáš Gregor, Miroslav Vařecha, Iva Gudernová, Bohumil Fafílek, Tomáš Bárta, Neha Basheer, Sara P. Abraham, Lukáš Bálek, Marketa Tomanova, Jana Kučerová, Juraj Bosák, David Potěšil, Jennifer Zieba, Jieun Song, Peter Koník, Sohyun Park, Iván Durán, Zbyněk Zdráhal, David Šmajs, Gert Jansen, Zheng Fu, Hyuk Wan Ko, Aleš Hampl, Lukáš Trantı́rek, Deborah Krakow, Pavel Krejčı́   +27 more
openalex   +1 more source

Degrading proteins at the primary cilium [PDF]

Nature Reviews Molecular Cell Biology, 2015
openaire   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang, Anh Hoang Pham, Mengjiao Luo, Masahito Ikawa, Haruhiko Miyata   +4 more
wiley   +1 more source

Molecular and structural perspectives on protein trafficking to the primary cilium membrane. [PDF]

Biochem Soc Trans
Reddy Palicharla V, Mukhopadhyay S.
europepmc   +1 more source