The primary cilium orchestrates chondrocyte mechanotransduction [PDF]
Osteoarthritis and Cartilage, 2012 CJ Haycraft +6 more
openaire +2 more sources
Evaluating Adverse Outcomes After Myringotomy or Tube Placement in Head and Neck Cancer
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Evaluate rates of adverse outcomes among patients with a history of head and neck cancer undergoing myringotomy with or without tube placement for middle ear effusion. Study Design Retrospective chart review. Setting Academic medical center.
Krithika Kuppusamy +7 more
wiley +1 more source
Metabolic Regulation and Energy Homeostasis through the Primary Cilium [PDF]
, 2014 Edwin C. Oh +2 more
openalex +1 more source
Evaluation of Benzo[cd]indol‐2(1H)‐ones as Downstream Hedgehog Pathway Inhibitors
ChemistryOpen, EarlyView.Benzo[cd]indol‐2(1H)‐one 1 inhibits the Hedgehog signaling pathway downstream of Suppressor of Fused, lowering cellular and ciliary GLI2 levels, and preventing GLI1 expression. A PROTAC‐based competition assay validated the cellular engagement of BET bromodomains, adding compound 1 to the growing set of epigenetic modulators of the Hedgehog signaling ...
Ioannis A. Tsakoumagkos +8 more
wiley +1 more source
Ophthalmic imaging in diabetic retinopathy: A review
Clinical &Experimental Ophthalmology, Volume 50, Issue 9, Page 1082-1096, December 2022., 2022 Abstract Retinal imaging has been a key tool in the diagnosis, evaluation, management and documentation of diabetic retinopathy (DR) and diabetic macular oedema (DMO) for many decades. Imaging technologies have rapidly evolved over the last few decades, yielding images with higher resolution and contrast with less time, effort and invasiveness.
Onnisa Nanegrungsunk +2 more
wiley +1 more source
Pediatric Discovery, EarlyView.ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang +4 more
wiley +1 more source
INPP5E interacts with AURKA, linking phosphoinositide signalling to primary cilium stability [PDF]
, 2014 Olga V. Plotnikova +7 more
openalex +1 more source
Primary Cilium-Dependent and -Independent Hedgehog Signaling Inhibits p16INK4A
, 2010 Cleo L. Bishop +8 more
openalex +1 more source
Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective
World Medical &Health Policy, EarlyView.ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley +1 more source
Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube. [PDF]
Proc Natl Acad Sci U S A, 2023 Shim S +5 more
europepmc +1 more source