Results 71 to 80 of about 4,151,372 (299)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Primary energy consumption in selected EU Countries compared to global trends

Open Chemistry, 2021
The article shows the consumption of primary energy carriers in selected European Union (EU) countries, including Poland. The trend of consumption of primary energy carriers was compared with the global trend, which is different from that observed in the
Olkuski Tadeusz, Suwała Wojciech, Wyrwa Artur, Zyśk Janusz, Tora Barbara   +4 more
doaj   +1 more source

Performance Evaluation of a Nearly Zero-Energy Office Building in Temperate Oceanic Climate Based on Field Measurements

Energies, 2022
This field study evaluated the building performance of a nearly zero-energy office building near Brussels, Belgium, located in the temperate climatic zone.
Deepak Amaripadath, Mirjana Velickovic, Shady Attia   +2 more
doaj   +1 more source

Comparison of AGASA data with CORSIKA simulation

, 1999
An interpretation of AGASA (Akeno Giant Air Shower Array) data by comparing the experimental results with the simulated ones by CORSIKA (COsmic Ray SImulation for KASCADE) has been made.
Barnett, Bird, Bird, Chiba, Dai, Dawson, Doi, Fletcher, Gaisser, Greisen, Greisen, Hayashida, Hayashida, Hayashida, Hayashida, Hillas, Kalmykov, Kasahara, Lawrence, M Nagano, Matsubara, Murzin, Nagano, Nagano, Ohoka, Sakaki, Shibata, Takeda, Takeda, Teshima, Yoshida, Zatsepin   +31 more
core   +1 more source

Measurement of the atmospheric muon charge ratio with the OPERA detector [PDF]

, 2010
The OPERA detector at the Gran Sasso underground laboratory (LNGS) was used to measure the atmospheric muon charge ratio in the TeV energy region. We analyzed 403069 atmospheric muons corresponding to 113.4 days of livetime during the 2008 CNGS run.
Agafonova, N., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Autiero, D., Badertscher, A., Bagulya, A., Bertolin, A., Besnier, M., Bick, D., Boyarkin, V., Bozza, C., Brugière, T., Brugnera, R., Brunetti, G., Buontempo, S., Cazes, A., Chaussard, L., Chernyavsky, M., Chiarella, V., Chon-Sen, N., Chukanov, A., Corso, F. Dal, Cozzi, M., D'Amato, G., D'Ambrosio, N., D'eclais, Y., De Lellis, G., De Serio, M., Di Capua, F., Di Ferdinando, D., Di Giovanni, A., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Ebert, J., Egorov, O., Enikeev, R., Ereditato, A., Esposito, L. S., Favier, J., Felici, G., Ferber, T., Fini, R., Frekers, D., Fukuda, T., Fukushima, C., Galkin, V. I., Garfagnini, A., Giacomelli, G., Giorgini, M., Goellnitz, C., Goldberg, J., Golubkov, D., Goncharova, L., Gornushkin, Y., Grella, G., Grianti, F., Guler, M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Hierholzer, M., Hoshino, K., Ieva, M., Jakovcic, K., Jollet, C., Juget, F., Kazuyama, M., Kim, S. H., Kimura, M., Klicek, B., Knuesel, J., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Kubota, H., Lavina, L. Scotto, Lazzaro, C., Lenkeit, J., Ljubicic, A., Longhin, A., Lutter, G., Malgin, A., Mandrioli, G., Marotta, A., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F., Meregaglia, A., Migliozzi, P., Mikado, S., Miyamoto, S., Monacelli, P., Morishima, K., Moser, U., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Naumov, D., Nikitina, V., Niwa, K., Nonoyama, Y., Ogawa, S., Olchevski, A., Oldorf, C., OPERA Collaboration, Orlova, G., Osedlo, V., Paniccia, M., Paoloni, A., Park, B. D., Park, I. G., Parzefall, W. Schmidt, Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pilipenko, V., Pistillo, C., Policastro, G., Polukhina, N., Pozzato, M., Pretzl, K., Publichenko, P., Pupilli, F., Rescigno, R., Roganova, T., Rokujo, H., Romano, G., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryasny, V., Ryazhskaya, O., Sato, O., Sato, Y., Schembri, A., Schroeder, H., Sheshukov, A., Shibuya, H., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Song, J. S., Spinetti, M., Stanco, L., Starkov, N., Stipcevic, M., Strauss, T., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tezuka, I., Tioukov, V., Tolun, P., Tran, T., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yakushev, V., Yoon, C. S., Yoshida, J., Yoshioka, T., Zaitsev, Y., Zemskova, S., Zghiche, A., Zimmermann, R.   +184 more
core   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A novel determination of density, temperature and symmetry energy for nuclear multi-fragmentation through primary fragment yield reconstruction [PDF]

, 2014
For the first time primary hot isotope distributions are experimentally reconstructed in intermediate heavy ion collisions and used with antisymmetrized molecular dynamics (AMD) calculations to determine density, temperature and symmetry energy ...
Barbui, M., Bonasera, A., Bottosso, C., Chen, Z., Hagel, K., Han, R., Huang, M., Jin, Z., Keutgen, T., Kim, E. J., Kowalski, S., Lin, W., Liu, J., Liu, X., Materna, T., Natowitz, J. B., Qin, L., Rodrigues, M. R. D., Sahu, P. K., Schmidt, K. J., Shi, F., Wada, R., Wang, J., Wuenschel, S., Xiao, G. Q., Zhang, S., Zheng, H.   +26 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source