Results 111 to 120 of about 19,641,486 (386)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Effective field theories for topological insulators by functional bosonization

open access: yes, 2013
Effective field theories that describes the dynamics of a conserved U(1) current in terms of "hydrodynamic" degrees of freedom of topological phases in condensed matter are discussed in general dimension $D=d+1$ using the functional bosonization ...
Chan, AtMa   +3 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Possibilities and limits of reduced primary tillage in organic farming [PDF]

open access: yes, 2002
In two organically cultivated field trials, located in Germany and Greece, effects of reduced primary tillage systems on root and shoot growth of cereals were investigated.
Dimitrios, Bilalis   +3 more
core  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Triploid Atlantic salmon (Salmo salar) may have increased risk of primary field outbreaks of infectious salmon anaemia. [PDF]

open access: yesJ Fish Dis, 2022
Aunsmo A   +7 more
europepmc   +1 more source

Cryogenic flux-concentrator [PDF]

open access: yes, 1969
Flux concentrator has high primary to secondary coupling efficiency enabling it to produce high magnetic fields.
Bailey, B. M., Brechna, H., Hill, D. A.
core   +1 more source

Conformal symmetry in non-local field theories

open access: yes, 2011
We have shown that a particular class of non-local free field theory has conformal symmetry in arbitrary dimensions. Using the local field theory counterpart of this class, we have found the Noether currents and Ward identities of the translation ...
A Cappelli   +20 more
core   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Mobilizing political support proved critical to a successful switch from tOPV to bOPV in Kano, Nigeria 2016

open access: yesBMC Public Health, 2018
Background Kano is one of the high-risk states for polio transmission in Northern Nigeria. The state reported more cases of wild polioviruses (WPVs) than any other state in the country.
Bashir Abba   +14 more
doaj   +1 more source

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