Results 111 to 120 of about 15,652,676 (359)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Human Immunodeficiency Virus Testing Trends Among Children in Kadoma City, Zimbabwe, 2015-2017

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Zambia is a cholera-endemic country and the epidemic in the capital, Lusaka, 2017-2018, caused more than 5,900 cases and 110 deaths. Low-income resident districts in Lusaka are known as hotspots for cholera outbreaks.
Chamunorwa Mhembe   +7 more
doaj   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

[Primary care: A definition of the field to develop research].

open access: yesRevue d'epidemiologie et de sante publique, 2018
Research in the field of primary care has dramatically increased in France in recent years, especially since 2013 with the introduction of primary care as a thematic priority for research proposals launched by the Ministry of Health (Direction générale de l'offre de soins).The RECaP (Research in Clinical Epidemiology and Public Health) network is a ...
Afonso, Mélanie   +12 more
openaire   +2 more sources

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Determinants of COVID-19 vaccine acceptance among residents of Ilorin metropolis, Nigeria, 2023: A community-based cluster survey

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: At least 70% of the eligible population in Nigeria must be vaccinated for the country to achieve herd immunity against COVID-19. Suboptimal vaccine acceptance could delay the timely achievement of this objective.
Abiodun Ebenezer Kolapo   +4 more
doaj   +1 more source

Prediction of Visual Field Progression in Patients with Primary Open-Angle Glaucoma, Mainly Including Normal Tension Glaucoma [PDF]

open access: gold, 2017
Koji Nitta   +11 more
openalex   +1 more source

A Field Evaluation of the Covid-19 Antigen Testing Regimen at a Primary Hospital in Ghana

open access: diamond, 2021
Prince Kenneth Homiah   +10 more
openalex   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Developing a digital phenotype to subdivide adult immunosuppressed COVID-19 outcomes within the English Primary Care Sentinel Network

open access: yesFrontiers in Immunology
BackgroundAdults classified as immunosuppressed have been disproportionately affected by the COVID-19 pandemic. Compared to the immunocompetent, certain patients are at increased risk of suboptimal vaccine response and adverse health outcomes if infected.
Meredith Leston   +13 more
doaj   +1 more source

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