Results 251 to 260 of about 2,834,721 (313)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The primary cilium at the helm: gatekeeper of TGF-β superfamily signaling in development, homeostasis, and disease. [PDF]

Biochem Soc Trans
Herrera-Cid C, Thomsen OK, Désarbre L, Marin RB, Doganli C, Pedersen LB, Larsen LA, Christensen ST.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Establishment of Breast Cancer Organoids: A Systematic Review and Meta-Analysis. [PDF]

Int J Breast Cancer
Rocha VM, Katayama MLH, Amorim LO, de Oliveira BD, Lopez RVM, Folgueira MAAK.   +5 more
europepmc   +1 more source

Overexpression of OsAGO18 Promotes Early Seedling Development and Root Elongation in Rice. [PDF]

Plants (Basel)
Tang C, Shan X, Liao X, Hu Q, Hu X, Wei R, Zhao H.   +6 more
europepmc   +1 more source

What if… cytokinin meets auxin in developing roots? The story behind root ring formation. [PDF]

Plant Cell
Di Fino LM.
europepmc   +1 more source

Can Phosphate-Solubilizing Microorganisms Unlock the Path to Sustainable Amazonian Forest Restoration? [PDF]

Curr Microbiol
Dos Santos SPA, da Rocha Nina Junior A, de Oliveira Pinho SS, de Carvalho JC, Dos Santos Viana C, da Costa KCP, Mangaravite É, Fernandes AV, Santana MF, Freitas CDT, de Carvalho Gonçalves JF.   +10 more
europepmc   +1 more source

Mechanisms of breast cancer dormancy in bone metastasis. [PDF]

Clin Exp Metastasis
Price ML, Zhou J, Le Maitre CL, Quayle LA, Ottewell PD.   +4 more
europepmc   +1 more source

AhR-Siglec-15 axis regulates lysosomal Ca2+ release for sonic hedgehog medulloblastoma growth via TRPML1. [PDF]

Protein Cell
Wang Z, Li S, Sun X, Wang D, Zhou Y, Zhou L, Chen J, Zhou N, Zhu Q, Liu J, Zhang G, Tong WM, Lv J, Huang B.   +13 more
europepmc   +1 more source