Results 91 to 100 of about 8,391,453 (340)

Direct healthcare costs of diabetes mellitus patients in Spain [PDF]

, 2003
Objectives. To estimate the healthcare resources spent by diabetic patients in Spain during the year 2002. Methods. The present work is a cost-of-illness study.
Lobo, Félix, Molina, Begoña, Monereo, Susana, Oliva Moreno, Juan   +3 more
core   +3 more sources

Effectiveness of telephone-based screening and triage during COVID-19 outbreak in the promoted primary healthcare system: a case study in Ardabil province, Iran

Journal of public health, 2020
Aims Screening services for early detection of patients is one of the important capabilities of the health system with a proper referral system. In the crisis of respiratory infection of Covid-19, screening based on symptoms is one of the key measures ...
N. Nejhaddadgar, A. Ziapour, Ghader Zakkipour, Jaffar Abbas, Mitra Abolfathi, M. Shabani   +5 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Telemonitoring of elderly with hypertension and type 2 diabetes at the primary care level: Protocol for a multicentric randomized controlled pilot study

Slovenian Journal of Public Health, 2022
Arterial hypertension (AH) and type 2 diabetes (T2D) represent a significant burden for the public health system, with an exceptionally high prevalence in patients aged ≥65 years.
Mihevc Matic, Zavrnik Črt, Mori Lukančič Majda, Virtič Tina, Prevolnik Rupel Valentina, Petek Šter Marija, Klemenc Ketiš Zalika, Poplas Susič Antonija   +7 more
doaj   +1 more source

Barriers and enablers to detection and management of chronic kidney disease in primary healthcare: a systematic review

BMC Nephrology, 2020
Background Chronic kidney disease (CKD) is growing population health concern worldwide, and with early identification and effective management, kidney disease progression can be slowed or prevented.
E. Neale, Justin Middleton, K. Lambert
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

National Analyses on Survival in Maltese Adult Patients on Renal Replacement Therapy Started During 2009–2012

European Medical Journal, 2019
Chronic kidney disease patients on maintenance dialysis (CKD 5D) experience major morbidity and mortality. No data on survival in Maltese dialysis patients exist; therefore, the aim of this study was to rigorously examine survival statistics in a ...
Baldacchino Ian, Debattista Sarah, Debattista Daniel, Balzan Gabriella, Abdilla Stefania, Baldacchino Lisa, Borg Gabriel, Buttigieg Sacha, Calleja Stafrace Nadine, Cutajar Karl, Galea Marica, Sciberras Whitney, Xerri Thelma, Camilleri Liberato, Farrugia Emanuel   +14 more
doaj  

Community health extension program of Ethiopia, 2003–2018: successes and challenges toward universal coverage for primary healthcare services

Globalization and Health, 2019
BackgroundEthiopia has been implementing a community health extension program (HEP) since 2003. We aimed to assess the successes and challenges of the HEP over time, and develop a framework that may assist the implementation of the program toward ...
Yibeltal Assefa, Y. Gelaw, P. Hill, B. Taye, W. Van Damme   +4 more
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Addressing low-value pharmacological prescribing in primary prevention of CVD through a structured evidence-based and theory-informed process for the design and testing of de-implementation strategies: the DE-imFAR study

Implementation Science, 2020
Background De-implementation or abandonment of ineffective or low-value healthcare is becoming a priority research field globally due to the growing empirical evidence of the high prevalence of such care and its impact in terms of patient safety and ...
Alvaro Sanchez, Jose Ignacio Pijoan, Susana Pablo, Marta Mediavilla, Rita Sainz de Rozas, Itxasne Lekue, Susana Gonzalez-Larragan, Gaspar Lantaron, Jon Argote, Arturo García-Álvarez, Pedro Maria Latorre, Christian D. Helfrich, Gonzalo Grandes   +12 more
doaj   +1 more source