Results 71 to 80 of about 1,515,766 (316)

Pap smear participation rates, primary healthcare and Indigenous women [PDF]

, 2003
To the Editor: As practitioners in a community-controlled Aboriginal and Torres Strait Islander primary healthcare centre, striving to better meet the healthcare needs of our community, we would like to offer some thoughts on a recent article by Coory et
Panaretto, Katie S., Manessis, Vivienne, Larkins, Sarah   +2 more
core  

An integrative literature review of pre-registration nursing students' attitudes and perceptions towards primary healthcare

, 2019
Background: There is a renewed focus on the role of primary healthcare within the health system due to an ageing population, increasing cost of acute healthcare services, and an emphasis on developing healthier communities.
Byfield, Zachary, Conway, Jane, East, Leah   +2 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Effective continuing professional development for translating shared decision making in primary care : a study protocol [PDF]

, 2010
Background: Shared decision making (SDM) is a process by which a healthcare choice is made jointly by the healthcare professional and the patient. SDM is the essential element of patient-centered care, a core concept of primary care.
Ferdjaoui-Moumjid, Nora, Rodriguez, Rosario, Mary Politi, Borduas, Francine, Griffiths Frances, Cornuz, J., Jackson, C., Cheater, Francine M., Mark Sullivan, Desroches Sophie, Cheater Francine M, Tanja Krones, Politi, M., Donner Banzhoff, N., Martin Härter, Norbert Donner-Banzhoff, Donner-Banzhoff, N., Sullivan Mark, Jacques, André, Coutu, M-F, Politi, Mary, Ferdjaoui-Moumjid Nora, Rousseau, Michel, Jacques André, Moumjid, Nora, Jackson, C, Rodriguez, R., Coutu, Marie-France, Jackson, Cath, Cornuz Jacques, Hilary Bekker, Bekker Hilary, Donner-Banzhoff, Norbert, Sophie Desroches, Nora Ferdjaoui-Moumjid, Marie-France Coutu, Ferdjaoui-Moumjid, N, Donner-Banzhof, Norbert, Borduas Francine, Rosario Rodriguez, Härter, M., Krones, Tanja, Härter, M, Légaré France, Coutu, M. F., Cheater, F M, Michel Rousseau, Bekker, H, Griffiths, Frances, Härter Martin, André Jacques, Jacques Cornuz, Jacques, A, Sullivan, M., Politi, M, Cornuz, Jacques, Krones, T, Desroches, Sophie, Coutu, M F, Rousseau Michel, Légaré, F., Stacey, Dawn, Politi Mary, Cath Jackson, Borduas, F., Rousseau, M, Donner-Banzhoff Norbert, Cornuz, J, Labrecque, M., Borduas, F, Jackson Cath, Rodriguez Rosario, Bekker, H., Coutu, M.F., Stacey, D, Härter, Martin, Cheater, Francine M, Krones, T; https://orcid.org/, Griffiths, F., Légaré, France, Cheater, F. M., Rousseau, M., Cheater, FM, Desroches, S, Sullivan, M, Ferdjaoui-Moumjid, N., Griffiths, F, Rodriguez, R, Donner-Banzhoff, N, France Légaré, Dawn Stacey, Cheater, F.M., Krones Tanja, Sullivan, Mark, Francine Borduas, Frances Griffiths, Francine M Cheater, Haerter, Martin, Labrecque, Michel, Labrecque Michel, Desroches, S., Michel Labrecque, Krones, T., Labrecque, M, Stacey, D., Coutu Marie-France, Jacques, A., Bekker, Hilary, Légaré, F, Stacey Dawn   +109 more
core   +1 more source

Analysis of Primary Healthcare Indicators

Mathematical and Computational Applications
This study aims to analyze the relationships between various health indicators, using an exploratory graph analysis, repeated measures correlation, and cluster construction. Primary healthcare is essential for providing continuous and comprehensive care, with indicators as crucial tools to identify and improve weaknesses in health units.
Ana Leonor Saraiva, Cristiana J. Silva, Jorge Cabral, José Pedro Antunes, Paula Rama, Sofia J. Pinheiro, Vera Afreixo   +6 more
openaire   +3 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The nurse practitioner's immuniser role in primary healthcare: A scoping review [PDF]

Aim(s) This scoping review aimed to explore and identify literature about the scope of practice for nurse practitioners working as immunisers in primary healthcare. Design The review was conducted according to the JBI scoping review framework.
Kauter, Kate, East, Leah, Schenfisch, Christine   +2 more
core   +1 more source

Scaling-up an integrated care for patients with non-communicable diseases: An analysis of healthcare barriers and facilitators in Slovenia and Belgium

Slovenian Journal of Public Health, 2021
Although the concept of integrated care for non-communicable diseases was introduced at the primary level to move from disease-centered to patient-centered care, it has only been partially implemented in European countries.
Zavrnik Črt, Danhieux Katrien, Monarres Miriam Hurtado, Stojnić Nataša, Lukančič Majda Mori, Martens Monika, Klemenc-Ketiš Zalika, Wouters Edwin, Olmen Josefien van, Poplas-Susič Antonija   +9 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source