Results 91 to 100 of about 1,515,766 (316)

How do older adults with multimorbidity navigate healthcare?: a qualitative study in Singapore

open access: yes, 2023
Background: Patients living with multimorbidity may require frequent visits to multiple healthcare institutions and to follow diverse medical regimens and advice.
Ding, Yew Yoong   +7 more
core   +1 more source

Physicians’ experiences of assessing and supporting fatigued patients in primary care: a focus group study

open access: yesBMC Primary Care
Background Fatigue is a common symptom in primary healthcare, affecting 10–30% of patients, and is associated with increased healthcare consumption and functional disability.
Conrad Samuelsson   +4 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Undermining India’s primary healthcare missions [PDF]

open access: yes
India’s Budget 2026–27 was presented on February 1 with much celebration and described as a transformative step toward inclusive growth. Finance Minister Nirmala Sitharaman reiterated the government’s commitment to ensuring access to resources and ...
Thakur, Avanindra Nath   +1 more
core  

Cost of heart failure in Swedish primary healthcare

open access: yes, 2005
Objectives. To calculate the cost for patients with heart failure (HF) in a primary healthcare setting. Design. Retrospective study of all available patient data during a period of one year. Setting.
Borgquist, Lars,   +3 more
core   +1 more source

Barriers and enablers to using evidence-based antibiotic prescription guidelines in primary care: a qualitative systematic review and synthesis using the theoretical domains framework

open access: yesImplementation Science Communications
Background Antibiotics are commonly overprescribed for upper respiratory tract infections (URTIs) in primary care against widely known guideline recommendations. To design an effective intervention to improve adherence to URTI guideline-based care, it is
Krystal Bursey   +8 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Facilitators and Barriers to Scaling-Up Integrated Care for Arterial Hypertension and Type 2 Diabetes in Slovenia: Qualitative Study

open access: yesSlovenian Journal of Public Health
Arterial hypertension and type 2 diabetes are significant contributors to global non-communicable disease-related mortality. Integrated care, centred on person-centred principles, aims to enhance healthcare quality and access, especially for vulnerable ...
ZAVRNIK Črt   +6 more
doaj   +1 more source

Isolated Hypogonadotropic Hypogonadism in a Young Woman with Primary Amenorrhoea

open access: yesOman Medical Journal
We describe a case of a young woman who presented with delayed secondary sexual development and primary amenorrhoea. She had low levels of oestradiol, follicle-stimulating hormone, and luteinizing hormone with normal levels of other pituitary hormones ...
Zalkha Al Kharusi   +6 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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