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THE DIAGNOSIS OF PRIMARY HYPERALDOSTERONISM
The Lancet, 1981An aldosterone-suppression test based on a simple method of extracellular-fluid volume expansion over three days reliably discriminated between patients with aldosterone-producing adenomas, idiopathic adrenal hyperplasia, and essential benign hypertension.
N J, Vaughan +6 more
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Primary Hyperaldosteronism in Pregnancy
Australian and New Zealand Journal of Medicine, 1982We report a case of primary hyperaldosteronism in a 37-year-old woman presenting early in pregnancy with hypertension and hypokalaemia. Plasma renin concentration was suppressed and unaffected by sodium restriction or upright posture at 16 and 35 weeks gestation, or seven days post-partum.
T G, Hammond +4 more
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Amiloride in primary hyperaldosteronism
Clinical Pharmacology and Therapeutics, 1982Amiloride is a potassium-sparing diuretic used in spontaneous and diuretic-induced hypokalemia. The effect of amiloride was studied prospectively in 12 patients with primary hyperaldosteronism. Four patients had unilateral adrenal adenomas and eight had bilateral adrenal hyperplasia. All patients were hypertensive and their mean plasma potassium levels
G T, Griffing +5 more
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Radiology in primary hyperaldosteronism
American Journal of Roentgenology, 1976Autonomous hypersecretion of aldosterone (primary hyperaldosteronism) is caused by either hyperplasia (usually bilateral) or an adenoma (frequently unilateral) of the adrenal cortex. Systemic hypertension due to an aldosteronoma is a potentially curable condition through surgical extirpation of the offending organ.
H Y, Yune +6 more
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Treatment of primary hyperaldosteronism
Medicina Clínica (English Edition), 2020Primary aldosteronism is associated with higher cardiovascular and renal morbidity and mortality than essential hypertension in age- and sex-matched patients with the same degree of blood pressure elevation. Therefore, it is essential to establish a specific treatment to avoid the deleterious effects of aldosterone excess.
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Surgery for Primary Hyperaldosteronism
Urologic Clinics of North America, 1989The most common underlying disorder in primary aldosteronism is a benign unilateral adenoma. Some cases, termed idiopathic, are secondary to bilateral adrenal hyperplasia, and a few are caused by adrenocortical carcinoma. The therapeutic alternatives are pharmacologic management with an aldosterone antagonist and surgical adrenalectomy.
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Hyperaldosteronism Among Black and White Subjects With Resistant Hypertension
Hypertension, 2002 Recent reports suggesting that the prevalence of primary hyperaldosteronism may be higher than historically thought have relied on an elevated plasma aldosterone concentration/plasma renin activity ratio to either diagnose or identify subjects at high ...
David A Calhoun
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Feline Primary Hyperaldosteronism
Veterinary Clinics of North America: Small Animal Practice, 2010Primary hyperaldosteronism (PHA) is being recognized more frequently in cats. Usual hallmarks of the disease include hypokalemia and systemic hypertension. Ultrasound frequently detects an abnormality in the affected adrenal gland. Diagnosis is based on increased plasma or serum aldosterone concentrations, particularly in the face of hypokalemia and ...
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