Results 91 to 100 of about 6,165,152 (262)

Bridging Ideal and Non-Ideal Theory

open access: yes, 2017
Many of the recent methodological debates within political theory have focused on the ideal/non-ideal theory distinction. While ideal theorists recognise the need to develop an account of the transition between the two levels of theorising, no general ...
Alexandru Volacu
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Zariski topology on the spectrum of intuitionistic fuzzy classical primary submodules [PDF]

open access: yesNotes on IFS
In this paper, we define and study the notion of intuitionistic fuzzy classical primary submodules over a unitary R-module M, where R is a commutative ring with unity.
Poonam Kumar Sharma
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

On f - prime radical in ordered semigroups

open access: yesOpen Mathematics, 2018
In this paper, we introduce the concepts of f-prime ideals, f-semiprime ideals and f-prime radicals in ordered semigroups. Furthermore, some results on f-prime radicals and f-primary decomposition of an ideal in an ordered semigroup are obtained.
Gu Ze
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Approximating ideal shapes with tight elements [PDF]

open access: yes, 2005
A variational approach is applied to the problem of finding the shortest curves in space separated by constant distance. Among particular extremal solutions are straight line, circular arc and double helix. Various knots and links may be assembled from
Starostin, E., Starostin, E.L.
core  

On 3-prime and quasi 3-primary ideals of ternary semirings [PDF]

open access: yes
The purpose of this paper is to introduce the concept of 3-prime ideal as a generalization of prime ideal. Further, we generalize the concepts of 3-prime ideal and primary ideal, namely as quasi 3-primary ideal in a commutative ternary semiring with zero.
Tamang, Nita   +2 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

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