Results 81 to 90 of about 725,736 (307)

Ideal Cardiovascular Health Metrics in Couples: A Community‐Based Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundDetermination of the correlation of ideal cardiovascular health variables among spousal or cohabitating partners may guide the development of couple‐based interventions to reduce cardiovascular disease risk.
Sebhat Erqou   +7 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Bridging Ideal and Non-Ideal Theory

open access: yes, 2017
Many of the recent methodological debates within political theory have focused on the ideal/non-ideal theory distinction. While ideal theorists recognise the need to develop an account of the transition between the two levels of theorising, no general ...
Alexandru Volacu
core   +1 more source

Primary Decomposition of Lattice Basis Ideals

open access: yesJournal of Symbolic Computation, 2000
Here is the authors' abstract: ``We study the primary decomposition of lattice basis ideals. These ideals are binomial ideals with generators given by the elements of a basis of a saturated integer lattice. We show that the minimal primes of such an ideal are completely determined by the sign pattern of the basis elements, while the embedded primes are
Serkan Hosten, Jay Shapiro
openaire   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Depth and Stanley depth of the edge ideals of the powers of paths and cycles

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
Let k be a positive integer. We compute depth and Stanley depth of the quotient ring of the edge ideal associated to the kth power of a path on n vertices.
Iqbal Zahid, Ishaq Muhammad
doaj   +1 more source

Does one size fit everyone? Replacement dose of levothyroxine in long-standing primary hypothyroidismin adults

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Objectives: The recommended starting dose of levothyroxine (LT4) in primary hypothyroidism is 1.6 μg/kg body weight and is based on presumption of minimal residual thyroid function in autoimmune hypothyroidism.
Rekha Singh
doaj   +1 more source

Low-Fee Private Schools in Developing Nations: Some Cautionary Remarks

open access: yesGlobal justice: Theory, Practice, Rhetoric, 2020
This paper examines and rejects two normative justifications for low-fee private schools (LFPS), whose expansion throughout the Global South in recent years has been significant.
Juan Espindola
doaj   +1 more source

Primary Decomposition of Ideals of Lattice Homomorphisms

open access: yesThe Electronic Journal of Combinatorics, 2018
For two given finite lattices $L$ and $M$, we introduce the ideal of lattice homomorphism $J(L,M)$, whose minimal monomial generators correspond to lattice homomorphisms $\phi : L\to M$. We show that $L$ is a distributive lattice if and only if the equidimensinal part of $J(L,M)$ is the same as the equidimensional part of the ideal of poset ...
Leila Sharifan   +2 more
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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