Results 51 to 60 of about 2,642,513 (283)

A mixed methods approach to exploring the moderating factors of implementation fidelity of the integrated chronic disease management model in South Africa

open access: yesBMC Health Services Research, 2020
Background Chronic care models like the Integrated Chronic Disease Management (ICDM) model strive to improve the efficiency and quality of care for patients with chronic diseases.
Limakatso Lebina   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Graded Weakly Strongly Quasi-Primary Ideals over Commutative Graded Rings

open access: yesMathematics
In this article, we introduce and examine the concept of graded weakly strongly quasi primary ideals. A proper graded ideal P of R is said to be a graded weakly strongly quasi primary (shortly, Gwsq-primary) ideal if whenever 0≠xy∈P, for some homogeneous
Azzh Saad Alshehry   +2 more
doaj   +1 more source

Gundersen Lutheran Health System: Performance Improvement Through Partnership [PDF]

open access: yes, 2009
Highlights Fund-defined attributes of an ideal system and best practices such as using data for benchmarking, increasing transparency, and driving improvement; investing in primary care and disease management; and hiring engineers to improve ...
Douglas McCarthy, Sarah Klein
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Rigid resolutions and big Betti numbers

open access: yes, 2003
In the first part of the paper we answer (positively) a question raised by the first author which has to do with some sort of rigity of the tail of resolution of an ideal. Let $I$ be a homogeneous ideal in a polynomial ring over a field of characteristic
Conca, Aldo   +2 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Fuzzy Weakly 2-Absorbing Ideals of a Lattice

open access: yesDiscussiones Mathematicae - General Algebra and Applications, 2022
As a generalization of the concept of a weakly prime ideal, we introduce the concepts of a fuzzy weak prime ideal, a fuzzy weakly 2-absorbing ideal of a lattice.
Nimbhorkar Shriram K., Patil Yogita S.
doaj   +1 more source

Symbolic powers of monomial ideals and Cohen-Macaulay vertex-weighted digraphs

open access: yes, 2018
In this paper we study irreducible representations and symbolic Rees algebras of monomial ideals. Then we examine edge ideals associated to vertex-weighted oriented graphs.
A Simis   +29 more
core   +1 more source

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