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Proof-of-concept study evaluating humoral primary immunodeficiencies via CJ:KREC ratio and serum BAFF level. [PDF]
Sci RepOchfeld E +4 more
europepmc +1 more source
Diagnostic yield of next-generation sequencing in suspect primary immunodeficiencies diseases: a systematic review and meta-analysis. [PDF]
Clin Exp MedChen Y +6 more
europepmc +1 more source
Primary immunodeficiency associated with chromosomal aberration – an ESID survey [PDF]
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The Primary Immunodeficiencies
New England Journal of Medicine, 1984The primary immunodeficiency disorders reflect abnormalities in the development and maturation of cells of the immune system. These defects result in an increased susceptibility to infection; recurrent pyogenic infections occur with defects of humoral immunity, and opportunistic infections with defects of cell-mediated immunity.
F S, Rosen, M D, Cooper, R J, Wedgwood
exaly +6 more sources
Journal of Allergy and Clinical Immunology, 2010
In the last years, advances in molecular genetics and immunology have resulted in the identification of a growing number of genes causing primary immunodeficiencies (PIDs) in human subjects and a better understanding of the pathophysiology of these disorders.
+8 more sources
In the last years, advances in molecular genetics and immunology have resulted in the identification of a growing number of genes causing primary immunodeficiencies (PIDs) in human subjects and a better understanding of the pathophysiology of these disorders.
+8 more sources