A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen +11 more
wiley +1 more source
Bone mineral density and trabecular bone score in adults with primary immunodeficiencies: a cross-sectional study. [PDF]
Nowakowska-Płaza A +6 more
europepmc +1 more source
Primary Immunodeficiencies in Children Initially Admitted with Gastrointestinal/Liver Manifestations. [PDF]
Cakir M +6 more
europepmc +1 more source
Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary +7 more
wiley +1 more source
Clinical Characteristics of IgE Deficiency Among Patients with Primary Immunodeficiencies: Findings from the USIDNET Registry. [PDF]
Jevtic D, Jakubowicz A, Ferastraoaru D.
europepmc +1 more source
Assessment of autoantibodies in paediatric population with primary immunodeficiencies: a pilot study. [PDF]
Pieniawska-Śmiech K +3 more
europepmc +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Immunity to Cryptosporidium: Lessons from Acquired and Primary Immunodeficiencies. [PDF]
Cohn IS +3 more
europepmc +1 more source
Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong +6 more
wiley +1 more source
ICF syndrome: An epigenetic paradigm for primary immunodeficiencies. [PDF]
Martins-Ferreira R, Ballestar E.
europepmc +1 more source

