Results 181 to 190 of about 30,549 (297)

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

open access: yesBMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai   +14 more
wiley   +1 more source

13q Deletion Syndrome Presenting with Lymphopenia Detected Through Newborn Screening for Primary Immunodeficiencies. [PDF]

open access: yesInt J Mol Sci
Efimova I   +14 more
europepmc   +1 more source

Primary Immunodeficiencies and Hematologic Malignancies: A Diagnostic Approach. [PDF]

open access: yesFront Immunol, 2022
Chandra S   +3 more
europepmc   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

open access: yesBMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu   +7 more
wiley   +1 more source

Primary immunodeficiencies.

open access: yesBulletin of the World Health Organization, 1972
Increased understanding of the nature and variety of immunodeficiency states in man is rapidly accumulating both from studies of human patients and from experimental work on the immune response in animals. Progress is evident in the development of diagnostic tests for deficiencies in both humoral and cellular mechanisms of immunity, and in the ...
openaire   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

Decreased IL-17-producing T<sub>H</sub> cells as a diagnostic marker for STAT signaling-related primary immunodeficiencies. [PDF]

open access: yesJ Allergy Clin Immunol Glob
Molnár E   +7 more
europepmc   +1 more source

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