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Dissecting Secondary Immunodeficiency: Identification of Primary Immunodeficiency within B-Cell Lymphoproliferative Disorders. [PDF]
J Clin ImmunolPalacios-Ortega M +28 more
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Primary Immunodeficiency and the Gut
Gastroenterology Clinics of North America, 2019This article presents the most common gastrointestinal, hepatic, and pancreatic manifestations of the primary immunodeficiency diseases, including the appropriate laboratory testing, endoscopic evaluation, and recommendations for further management.
David, Schwimmer, Sarah, Glover
exaly +3 more sources
Primary Immunodeficiency and Rhinosinusitis
Immunology and Allergy Clinics of North America, 2020Refractory rhinosinusitis can be related to comorbid medical conditions, including primary immunodeficiency. Given the prevalence of immunodeficiency, clinicians should have a low threshold to consider these diagnoses. This article reviews primary immunodeficiencies contributing to chronic rhinosinusitis, including a proposed diagnostic work-up and the
Camille, Huwyler +2 more
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The Primary Immunodeficiencies
New England Journal of Medicine, 1984The primary immunodeficiency disorders reflect abnormalities in the development and maturation of cells of the immune system. These defects result in an increased susceptibility to infection; recurrent pyogenic infections occur with defects of humoral immunity, and opportunistic infections with defects of cell-mediated immunity.
F S, Rosen, M D, Cooper, R J, Wedgwood
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Journal of Allergy and Clinical Immunology, 2010
In the last years, advances in molecular genetics and immunology have resulted in the identification of a growing number of genes causing primary immunodeficiencies (PIDs) in human subjects and a better understanding of the pathophysiology of these disorders.
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In the last years, advances in molecular genetics and immunology have resulted in the identification of a growing number of genes causing primary immunodeficiencies (PIDs) in human subjects and a better understanding of the pathophysiology of these disorders.
openaire +6 more sources
Primary Immunodeficiency and Thrombocytopenia
International Reviews of Immunology, 2021Primary immunodeficiency (PID) or Inborn errors of immunity (IEI) refers to a heterogeneous group of disorders characterized by immune system impairment. Although patients with IEI manifest highly variable symptoms, the most common clinical manifestations are recurrent infections, autoimmunity and malignancies.
Maryam Mohtashami +4 more
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Malakoplakia and Primary Immunodeficiency
The Journal of Pediatrics, 2014Malakoplakia, a rare granulomatous disease caused by impaired macrophage response, has been reported only rarely in children. We report 3 unique cases, with lesions occurring in unusual locations in children with primary immune deficiencies.
Sydney R. Archer +8 more
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Cytomegalovirus in primary immunodeficiency
Current Opinion in Infectious Diseases, 2021Purpose of review Cytomegalovirus (CMV) infection and disease are well described in the setting of secondary immunodeficiency. Less is known about CMV in the context of primary immunodeficiencies (PIDs), where inborn errors in one or more arms of the immune system result in variable degrees of CMV susceptibility.
Jack, Godsell +6 more
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Approach to primary immunodeficiency
Allergy and Asthma Proceedings, 2019Primary immunodeficiency diseases are inherited defects of the innate or adaptive arms of the immune system that lead to an increase in the incidence, frequency, or severity of infections and/or immune dysregulation. There may be defects in the adaptive arm of the immune system, including combined immunodeficiencies and antibody deficiency syndromes ...
Ashley L, Devonshire, Melanie, Makhija
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