Results 191 to 200 of about 495,905 (303)

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

A Critical View of Specific Antibody Deficiencies

Frontiers in Immunology, 2019
Ricardo U. Sorensen, Ricardo U. Sorensen, Ricardo U. Sorensen   +2 more
doaj   +1 more source

Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency. [PDF]

Mol Ther Nucleic Acids
Fiduccia I, Vitale E, Varrica R, Ricci D, Marino S, Zito A, Pace A, Colige A, Moutschen M, Borutzki Y, Bileck A, Meier-Menches SM, Lentini L, Pibiri I.   +13 more
europepmc   +1 more source

Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park, Alexander Bevacqua, Mingyang Cui, Marina Nichols, Jianzhu Chen, Jongyoon Han   +5 more
wiley   +1 more source

Corrigendum to “Immune defects in active mycobacterial diseases in patients with primary immunodeficiency diseases (PIDs)”

Journal of the Formosan Medical Association, 2012
Wen-I. Lee, Jing-Long Huang, Kuo-Wei Yeh, Tang-Her Jaing, Tzou-Yien Lin, Yhu-Chering Huang, Cheng-Hsun Chiu   +6 more
doaj   +1 more source

Progressive multifocal leukoencephalopathy in a young adult with DOCK8 deficiency: a case of JC virus reactivation in primary immunodeficiency. [PDF]

J Neurovirol
Naydovich L, Berger JR, Milutinovic PS.
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Novel variants related to extreme elevation of serum IgE in Vietnamese patients with primary immunodeficiency: Case report. [PDF]

Medicine (Baltimore)
Huong LTM, Lien NTK, Van Anh NT, Dien TM, Mai NTP, Ngoc ND, Thu NM, Ngan NTT, Hien NT, Van Tung N, Hoang NH.   +10 more
europepmc   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Distinct pulmonary pathophysiological mechanisms in COPD, bronchiectasis, and primary immunodeficiency: a multi-omics investigation of disease heterogeneity via sputum and blood profiling. [PDF]

Respir Res
Graeter S, Gonzalez-Jaramillo N, Wildschut MHE, Capriotti L, Saxenhofer M, Robador JR, Monaghan K, Woodman N, Field J, Wilson N, Rees M, Hauswald M, Roca CP, Feussner A, Schulze I, Stewart A, Schaub A, Chan S, Douglass JA, Schnell A.   +19 more
europepmc   +1 more source