Objective Quantify cytokines in cerebrospinal fluid (CSF) of virologically suppressed people with HIV (PWH) and people without HIV (PWoH) and correlate these with neuroimaging, neuropsychometric (NP), and neurodegenerative measurements. Methods CSF samples were collected from virologically suppressed PWH and demographically matched PWoH under a natural
Jack Peterson +13 more
wiley +1 more source
Understanding the disease burden and unmet needs of patients with primary immunodeficiency in China: A quantitative study. [PDF]
Li L, Chen Y, He Z, Li Q, Huang R.
europepmc +1 more source
Comparison of hyaluronidase-facilitated subcutaneous immunoglobulin 10% pharmacokinetics in pediatric and adult patients with primary immunodeficiency: an analysis of three phase 3 clinical trials. [PDF]
Li Z, Ballesteros-Perez A.
europepmc +1 more source
Clinical Evaluation of Pharmacokinetics, Efficacy, and Safety of a 10% Immunoglobulin in Primary Immunodeficiency Disease (CARES10 Study). [PDF]
Roifman CM +14 more
europepmc +1 more source
Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary +7 more
wiley +1 more source
Immunoglobulin replacement therapy in primary immunodeficiency disorders: Pragmatic review and evidence mapping. [PDF]
Carr E +8 more
europepmc +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Genetic and epidemiological patterns of primary immunodeficiency diseases in Eastern Iranian patients. [PDF]
Salehi M +6 more
europepmc +1 more source
Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong +6 more
wiley +1 more source
Adverse reactions to intravenous immunoglobulin in primary immunodeficiency: a retrospective analysis. [PDF]
Demirel F +4 more
europepmc +1 more source

