Results 151 to 160 of about 495,905 (303)

Molecular genetics of common variable immunodeficiency

, 2017
Bogaert, Delfien, De Baere, Elfride, Dullaers, Melissa, Haerynck, Filomeen   +3 more
core   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

Understanding the disease burden and unmet needs of patients with primary immunodeficiency in China: A quantitative study. [PDF]

Intractable Rare Dis Res
Li L, Chen Y, He Z, Li Q, Huang R.
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Immunoglobulin replacement therapy in primary immunodeficiency disorders: Pragmatic review and evidence mapping. [PDF]

J Allergy Clin Immunol Glob
Carr E, McCool R, Ferrante di Ruffano L, Arber M, Reddish K, Burns J, Holcomb-Selbert R, Abdalgani M, Orange JS.   +8 more
europepmc   +1 more source

Development of immunocompetent models for primary and metastatic ER+ breast cancer

Animal Models and Experimental Medicine, EarlyView.
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull, Jody Hazlett, Emily Schulpen, Sophie Tunnicliffe, Alexander D. McLellan, Anita K. Dunbier   +5 more
wiley   +1 more source

Comparison of clinical characteristics in primary immunodeficiency patients based on the presence of autoimmunity or autoinflammation. [PDF]

Allergy Asthma Proc
Kolak S, Çölkesen F, Gerek ME, Sağun F, Harman E, Savaş ŞA, Arslan Ş.   +6 more
europepmc   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Nonhuman Primate Models for HIV Cure Research [PDF]

, 2012
Cristian Apetrei, Ivona Pandrea, John W. Mellors, Richard A. Koup   +3 more
core   +3 more sources

Pharmacokinetics of hyaluronidase-facilitated subcutaneous immunoglobulin 10% in pediatric patients with primary immunodeficiency disease. [PDF]

Immunother Adv
Li Z, Teng Y, Russo-Schwarzbaum S, McCoy B.   +3 more
europepmc   +1 more source